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Calcium sensitive ring-like oligomers formed by synaptotagmin.
Wang J, Bello O, Auclair SM, Wang J, Coleman J, Pincet F, Krishnakumar SS, Sindelar CV, Rothman JE. Wang J, et al. Among authors: krishnakumar ss. Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13966-71. doi: 10.1073/pnas.1415849111. Epub 2014 Sep 8. Proc Natl Acad Sci U S A. 2014. PMID: 25201968 Free PMC article.
Ring-like oligomers of Synaptotagmins and related C2 domain proteins.
Zanetti MN, Bello OD, Wang J, Coleman J, Cai Y, Sindelar CV, Rothman JE, Krishnakumar SS. Zanetti MN, et al. Among authors: krishnakumar ss. Elife. 2016 Jul 19;5:e17262. doi: 10.7554/eLife.17262. Elife. 2016. PMID: 27434670 Free PMC article.
Homozygous mutations in VAMP1 cause a presynaptic congenital myasthenic syndrome.
Salpietro V, Lin W, Delle Vedove A, Storbeck M, Liu Y, Efthymiou S, Manole A, Wiethoff S, Ye Q, Saggar A, McElreavey K, Krishnakumar SS; SYNAPS Study Group; Pitt M, Bello OD, Rothman JE, Basel-Vanagaite L, Hubshman MW, Aharoni S, Manzur AY, Wirth B, Houlden H. Salpietro V, et al. Among authors: krishnakumar ss. Ann Neurol. 2017 Apr;81(4):597-603. doi: 10.1002/ana.24905. Epub 2017 Mar 29. Ann Neurol. 2017. PMID: 28253535 Free PMC article.
Dilation of fusion pores by crowding of SNARE proteins.
Wu Z, Bello OD, Thiyagarajan S, Auclair SM, Vennekate W, Krishnakumar SS, O'Shaughnessy B, Karatekin E. Wu Z, et al. Among authors: krishnakumar ss. Elife. 2017 Mar 27;6:e22964. doi: 10.7554/eLife.22964. Elife. 2017. PMID: 28346138 Free PMC article.
Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses.
Michalski N, Goutman JD, Auclair SM, Boutet de Monvel J, Tertrais M, Emptoz A, Parrin A, Nouaille S, Guillon M, Sachse M, Ciric D, Bahloul A, Hardelin JP, Sutton RB, Avan P, Krishnakumar SS, Rothman JE, Dulon D, Safieddine S, Petit C. Michalski N, et al. Among authors: krishnakumar ss. Elife. 2017 Nov 7;6:e31013. doi: 10.7554/eLife.31013. Elife. 2017. PMID: 29111973 Free PMC article.
56 results