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Hypoxia converts human macrophages into triglyceride-loaded foam cells.
Boström P, Magnusson B, Svensson PA, Wiklund O, Borén J, Carlsson LM, Ståhlman M, Olofsson SO, Hultén LM. Boström P, et al. Among authors: boren j. Arterioscler Thromb Vasc Biol. 2006 Aug;26(8):1871-6. doi: 10.1161/01.ATV.0000229665.78997.0b. Epub 2006 Jun 1. Arterioscler Thromb Vasc Biol. 2006. PMID: 16741148
The SNARE protein SNAP23 and the SNARE-interacting protein Munc18c in human skeletal muscle are implicated in insulin resistance/type 2 diabetes.
Boström P, Andersson L, Vind B, Håversen L, Rutberg M, Wickström Y, Larsson E, Jansson PA, Svensson MK, Brånemark R, Ling C, Beck-Nielsen H, Borén J, Højlund K, Olofsson SO. Boström P, et al. Among authors: boren j. Diabetes. 2010 Aug;59(8):1870-8. doi: 10.2337/db09-1503. Epub 2010 May 11. Diabetes. 2010. Retraction in: Diabetes. 2017 May;66(5):1426. doi: 10.2337/db17-rt05a. PMID: 20460426 Free PMC article. Retracted.
PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals.
Burza MA, Pirazzi C, Maglio C, Sjöholm K, Mancina RM, Svensson PA, Jacobson P, Adiels M, Baroni MG, Borén J, Ginanni Corradini S, Montalcini T, Sjöström L, Carlsson LM, Romeo S. Burza MA, et al. Among authors: boren j. Dig Liver Dis. 2012 Dec;44(12):1037-41. doi: 10.1016/j.dld.2012.05.006. Epub 2012 Jun 15. Dig Liver Dis. 2012. PMID: 22704398 Clinical Trial.
The IRS1 rs2943641 variant and risk of future cancer among morbidly obese individuals.
Maglio C, Ericson U, Burza MA, Mancina RM, Pirazzi C, Assarsson JA, Sjöholm K, Baroni MG, Svensson PA, Montalcini T, Pujia A, Sjöström L, Wiklund O, Carlsson LM, Borén J, Orho-Melander M, Romeo S. Maglio C, et al. Among authors: boren j. J Clin Endocrinol Metab. 2013 Apr;98(4):E785-9. doi: 10.1210/jc.2012-2831. Epub 2013 Feb 15. J Clin Endocrinol Metab. 2013. PMID: 23418314
481 results