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Inhibition of bone morphogenetic protein signal transduction prevents the medial vascular calcification associated with matrix Gla protein deficiency.
Malhotra R, Burke MF, Martyn T, Shakartzi HR, Thayer TE, O'Rourke C, Li P, Derwall M, Spagnolli E, Kolodziej SA, Hoeft K, Mayeur C, Jiramongkolchai P, Kumar R, Buys ES, Yu PB, Bloch KD, Bloch DB. Malhotra R, et al. Among authors: bloch db, bloch kd. PLoS One. 2015 Jan 20;10(1):e0117098. doi: 10.1371/journal.pone.0117098. eCollection 2015. PLoS One. 2015. PMID: 25603410 Free PMC article.
Hepcidin Deficiency Protects Against Atherosclerosis.
Malhotra R, Wunderer F, Barnes HJ, Bagchi A, Buswell MD, O'Rourke CD, Slocum CL, Ledsky CD, Peneyra KM, Sigurslid H, Corman B, Johansson KB, Rhee DK, Bloch KD, Bloch DB. Malhotra R, et al. Among authors: bloch kd. Arterioscler Thromb Vasc Biol. 2019 Feb;39(2):178-187. doi: 10.1161/ATVBAHA.118.312215. Arterioscler Thromb Vasc Biol. 2019. PMID: 30587002 Free PMC article.
Nitric oxide regulates pulmonary vascular smooth muscle cell expression of the inducible cAMP early repressor gene.
Steinbicker AU, Liu H, Jiramongkolchai K, Malhotra R, Choe EY, Busch CJ, Graveline AR, Kao SM, Nagasaka Y, Ichinose F, Buys ES, Brouckaert P, Zapol WM, Bloch KD. Steinbicker AU, et al. Among authors: bloch kd. Nitric Oxide. 2011 Oct 30;25(3):294-302. doi: 10.1016/j.niox.2011.05.006. Epub 2011 May 27. Nitric Oxide. 2011. PMID: 21642009 Free PMC article.
Targeting BMP signalling in cardiovascular disease and anaemia.
Morrell NW, Bloch DB, ten Dijke P, Goumans MJ, Hata A, Smith J, Yu PB, Bloch KD. Morrell NW, et al. Among authors: bloch db, bloch kd. Nat Rev Cardiol. 2016 Feb;13(2):106-20. doi: 10.1038/nrcardio.2015.156. Epub 2015 Oct 13. Nat Rev Cardiol. 2016. PMID: 26461965 Free PMC article. Review.
BMP type I receptor ALK2 is required for angiotensin II-induced cardiac hypertrophy.
Shahid M, Spagnolli E, Ernande L, Thoonen R, Kolodziej SA, Leyton PA, Cheng J, Tainsh RE, Mayeur C, Rhee DK, Wu MX, Scherrer-Crosbie M, Buys ES, Zapol WM, Bloch KD, Bloch DB. Shahid M, et al. Among authors: bloch db, bloch kd. Am J Physiol Heart Circ Physiol. 2016 Apr 15;310(8):H984-94. doi: 10.1152/ajpheart.00879.2015. Epub 2016 Feb 12. Am J Physiol Heart Circ Physiol. 2016. PMID: 26873969 Free PMC article.
The Role of Bone Morphogenetic Protein Signaling in Non-Alcoholic Fatty Liver Disease.
Thayer TE, Lino Cardenas CL, Martyn T, Nicholson CJ, Traeger L, Wunderer F, Slocum C, Sigurslid H, Shakartzi HR, O'Rourke C, Shelton G, Buswell MD, Barnes H, Neitzel LR, Ledsky CD, Li JP, Burke MF, Farber-Eger E, Perrien DS, Kumar R, Corey KE, Wells QS, Bloch KD, Hong CC, Bloch DB, Malhotra R. Thayer TE, et al. Among authors: bloch kd. Sci Rep. 2020 Jun 19;10(1):9831. doi: 10.1038/s41598-020-66770-8. Sci Rep. 2020. PMID: 32561790 Free PMC article.
243 results