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STAT3 modulates β-cell cycling in injured mouse pancreas and protects against DNA damage.
De Groef S, Renmans D, Cai Y, Leuckx G, Roels S, Staels W, Gradwohl G, Baeyens L, Heremans Y, Martens GA, De Leu N, Sojoodi M, Van de Casteele M, Heimberg H. De Groef S, et al. Among authors: leuckx g. Cell Death Dis. 2016 Jun 23;7(6):e2272. doi: 10.1038/cddis.2016.171. Cell Death Dis. 2016. PMID: 27336716 Free PMC article.
Neurogenin 3+ cells contribute to β-cell neogenesis and proliferation in injured adult mouse pancreas.
Van de Casteele M, Leuckx G, Baeyens L, Cai Y, Yuchi Y, Coppens V, De Groef S, Eriksson M, Svensson C, Ahlgren U, Ahnfelt-Rønne J, Madsen OD, Waisman A, Dor Y, Jensen JN, Heimberg H. Van de Casteele M, et al. Among authors: leuckx g. Cell Death Dis. 2013 Mar 7;4(3):e523. doi: 10.1038/cddis.2013.52. Cell Death Dis. 2013. PMID: 23470530 Free PMC article.
Reprogramming of human pancreatic exocrine cells to β-like cells.
Lemper M, Leuckx G, Heremans Y, German MS, Heimberg H, Bouwens L, Baeyens L. Lemper M, et al. Among authors: leuckx g. Cell Death Differ. 2015 Jul;22(7):1117-30. doi: 10.1038/cdd.2014.193. Epub 2014 Dec 5. Cell Death Differ. 2015. PMID: 25476775 Free PMC article.
Accessory cells for β-cell transplantation.
Staels W, De Groef S, Heremans Y, Coppens V, Van Gassen N, Leuckx G, Van de Casteele M, Van Riet I, Luttun A, Heimberg H, De Leu N. Staels W, et al. Among authors: leuckx g. Diabetes Obes Metab. 2016 Feb;18(2):115-24. doi: 10.1111/dom.12556. Epub 2015 Oct 9. Diabetes Obes Metab. 2016. PMID: 26289770 Review.
Making β(-like)-cells from exocrine pancreas.
Staels W, De Groef S, Bussche L, Leuckx G, Van de Casteele M, De Leu N, Baeyens L, Heremans Y, Heimberg H. Staels W, et al. Among authors: leuckx g. Diabetes Obes Metab. 2016 Sep;18 Suppl 1:144-51. doi: 10.1111/dom.12725. Diabetes Obes Metab. 2016. PMID: 27615144 Review.
ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling.
Pinho AV, Van Bulck M, Chantrill L, Arshi M, Sklyarova T, Herrmann D, Vennin C, Gallego-Ortega D, Mawson A, Giry-Laterriere M, Magenau A, Leuckx G, Baeyens L, Gill AJ, Phillips P, Timpson P, Biankin AV, Wu J, Rooman I. Pinho AV, et al. Among authors: leuckx g. Nat Commun. 2018 Nov 30;9(1):5083. doi: 10.1038/s41467-018-07497-z. Nat Commun. 2018. PMID: 30504844 Free PMC article.
Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease.
Martens S, Coolens K, Van Bulck M, Arsenijevic T, Casamitjana J, Fernandez Ruiz A, El Kaoutari A, Martinez de Villareal J, Madhloum H, Esni F, Heremans Y, Leuckx G, Heimberg H, Bouwens L, Jacquemin P, De Paep DL, In't Veld P, D'Haene N, Bouchart C, Dusetti N, Van Laethem JL, Waelput W, Lefesvre P, Real FX, Rovira M, Rooman I. Martens S, et al. Among authors: leuckx g. Gut. 2021 Jul 30;71(10):2030-42. doi: 10.1136/gutjnl-2020-322874. Online ahead of print. Gut. 2021. PMID: 34330784 Free PMC article.
Retraction Note: Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice.
Baeyens L, Lemper M, Leuckx G, De Groef S, Bonfanti P, Stangé G, Shemer R, Nord C, Scheel DW, Pan FC, Ahlgren U, Gu G, Stoffers DA, Dor Y, Ferrer J, Gradwohl G, Wright CVE, Van de Casteele M, German MS, Bouwens L, Heimberg H. Baeyens L, et al. Among authors: leuckx g. Nat Biotechnol. 2020 Mar;38(3):374. doi: 10.1038/s41587-020-0426-2. Nat Biotechnol. 2020. PMID: 32066957 Free PMC article.
31 results