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Attenuation of colistin bactericidal activity by high inoculum of Pseudomonas aeruginosa characterized by a new mechanism-based population pharmacodynamic model.
Bulitta JB, Yang JC, Yohonn L, Ly NS, Brown SV, D'Hondt RE, Jusko WJ, Forrest A, Tsuji BT. Bulitta JB, et al. Among authors: ly ns. Antimicrob Agents Chemother. 2010 May;54(5):2051-62. doi: 10.1128/AAC.00881-09. Epub 2010 Mar 8. Antimicrob Agents Chemother. 2010. PMID: 20211900 Free PMC article.
Pharmacodynamic variability beyond that explained by MICs.
Soon RL, Ly NS, Rao G, Wollenberg L, Yang K, Tsuji B, Forrest A. Soon RL, et al. Among authors: ly ns. Antimicrob Agents Chemother. 2013 Apr;57(4):1730-5. doi: 10.1128/AAC.01224-12. Epub 2013 Jan 28. Antimicrob Agents Chemother. 2013. PMID: 23357773 Free PMC article.
New dosing strategies for an old antibiotic: pharmacodynamics of front-loaded regimens of colistin at simulated pharmacokinetics in patients with kidney or liver disease.
Rao GG, Ly NS, Haas CE, Garonzik S, Forrest A, Bulitta JB, Kelchlin PA, Holden PN, Nation RL, Li J, Tsuji BT. Rao GG, et al. Among authors: ly ns. Antimicrob Agents Chemother. 2014;58(3):1381-8. doi: 10.1128/AAC.00327-13. Epub 2013 Dec 16. Antimicrob Agents Chemother. 2014. PMID: 24342636 Free PMC article.
25 results