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Page 1
Discovery of novel 2',4'-dimethyl-[4,5'-bithiazol]-2-yl amino derivatives as orally bioavailable TRPV4 antagonists for the treatment of pain: Part 2.
Tsuno N, Yukimasa A, Yoshida O, Suzuki S, Nakai H, Ogawa T, Fujiu M, Takaya K, Nozu A, Yamaguchi H, Matsuda H, Funaki S, Nishimura Y, Ito T, Nagamatsu D, Asaki T, Horita N, Yamamoto M, Hinata M, Soga M, Imai M, Morioka Y, Kanemasa T, Sakaguchi G, Iso Y. Tsuno N, et al. Among authors: suzuki s. Bioorg Med Chem Lett. 2016 Oct 15;26(20):4936-4941. doi: 10.1016/j.bmcl.2016.09.014. Epub 2016 Sep 7. Bioorg Med Chem Lett. 2016. PMID: 27634196
Pharmacological evaluation of novel (6-aminopyridin-3-yl)(4-(pyridin-2-yl)piperazin-1-yl) methanone derivatives as TRPV4 antagonists for the treatment of pain.
Tsuno N, Yukimasa A, Yoshida O, Suzuki S, Nakai H, Ogawa T, Fujiu M, Takaya K, Nozu A, Yamaguchi H, Matsuda H, Funaki S, Yamanada N, Tanimura M, Nagamatsu D, Asaki T, Horita N, Yamamoto M, Hinata M, Soga M, Imai M, Morioka Y, Kanemasa T, Sakaguchi G, Iso Y. Tsuno N, et al. Among authors: suzuki s. Bioorg Med Chem. 2017 Apr 1;25(7):2177-2190. doi: 10.1016/j.bmc.2017.02.047. Epub 2017 Mar 1. Bioorg Med Chem. 2017. PMID: 28284871
Trifluoromethyl Dihydrothiazine-Based β-Secretase (BACE1) Inhibitors with Robust Central β-Amyloid Reduction and Minimal Covalent Binding Burden.
Anan K, Iso Y, Oguma T, Nakahara K, Suzuki S, Yamamoto T, Matsuoka E, Ito H, Sakaguchi G, Ando S, Morimoto K, Kanegawa N, Kido Y, Kawachi T, Fukushima T, Teisman A, Urmaliya V, Dhuyvetter D, Borghys H, Austin N, Van Den Bergh A, Verboven P, Bischoff F, Gijsen HJM, Yamano Y, Kusakabe K. Anan K, et al. Among authors: suzuki s. ChemMedChem. 2019 Nov 20;14(22):1894-1910. doi: 10.1002/cmdc.201900478. Epub 2019 Nov 12. ChemMedChem. 2019. PMID: 31657130
Discovery of an Extremely Potent Thiazine-Based β-Secretase Inhibitor with Reduced Cardiovascular and Liver Toxicity at a Low Projected Human Dose.
Tadano G, Komano K, Yoshida S, Suzuki S, Nakahara K, Fuchino K, Fujimoto K, Matsuoka E, Yamamoto T, Asada N, Ito H, Sakaguchi G, Kanegawa N, Kido Y, Ando S, Fukushima T, Teisman A, Urmaliya V, Dhuyvetter D, Borghys H, Van Den Bergh A, Austin N, Gijsen HJM, Yamano Y, Iso Y, Kusakabe KI. Tadano G, et al. Among authors: suzuki s. J Med Chem. 2019 Oct 24;62(20):9331-9337. doi: 10.1021/acs.jmedchem.9b01140. Epub 2019 Oct 8. J Med Chem. 2019. PMID: 31549838
Structure-Based Approaches to Improving Selectivity through Utilizing Explicit Water Molecules: Discovery of Selective β-Secretase (BACE1) Inhibitors over BACE2.
Fujimoto K, Yoshida S, Tadano G, Asada N, Fuchino K, Suzuki S, Matsuoka E, Yamamoto T, Yamamoto S, Ando S, Kanegawa N, Tonomura Y, Ito H, Moechars D, Rombouts FJR, Gijsen HJM, Kusakabe KI. Fujimoto K, et al. Among authors: suzuki s. J Med Chem. 2021 Mar 25;64(6):3075-3085. doi: 10.1021/acs.jmedchem.0c01858. Epub 2021 Mar 15. J Med Chem. 2021. PMID: 33719429
A non-methanogenic archaeon within the order Methanocellales.
Suzuki S, Ishii S, Chadwick GL, Tanaka Y, Kouzuma A, Watanabe K, Inagaki F, Albertsen M, Nielsen PH, Nealson KH. Suzuki S, et al. Nat Commun. 2024 Jun 13;15(1):4858. doi: 10.1038/s41467-024-48185-5. Nat Commun. 2024. PMID: 38871712 Free PMC article.
The Validation of the Japanese Version of the Scoliosis Research Society-30 Questionnaire for Adolescent Idiopathic Scoliosis Patients.
Arima H, Yamato Y, Shibata Y, Oba H, Takahashi J, Watanabe K, Sugawara R, Takeshita K, Omura T, Carreon L, Arai Y, Asada T, Demura S, Doi T, Matsumura A, Suzuki S, Takahashi S, Takeuchi T, Ueda H, Hosogane N. Arima H, et al. Among authors: suzuki s. Spine Surg Relat Res. 2024 Feb 14;8(3):280-286. doi: 10.22603/ssrr.2023-0202. eCollection 2024 May 27. Spine Surg Relat Res. 2024. PMID: 38868795 Free PMC article.
Development and Validation of Machine Learning-Based Predictive Model for Prolonged Hospital Stay after Decompression Surgery for Lumbar Spinal Canal Stenosis.
Yagi M, Yamamoto T, Iga T, Ogura Y, Suzuki S, Ozaki M, Takahashi Y, Tsuji O, Nagoshi N, Kono H, Ogawa J, Matsumoto M, Nakamura M, Watanabe K; Keio Spine Research Group. Yagi M, et al. Among authors: suzuki s. Spine Surg Relat Res. 2024 Feb 14;8(3):315-321. doi: 10.22603/ssrr.2023-0255. eCollection 2024 May 27. Spine Surg Relat Res. 2024. PMID: 38868786 Free PMC article.
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