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Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models.
Davis MI, Pragani R, Fox JT, Shen M, Parmar K, Gaudiano EF, Liu L, Tanega C, McGee L, Hall MD, McKnight C, Shinn P, Nelson H, Chattopadhyay D, D'Andrea AD, Auld DS, DeLucas LJ, Li Z, Boxer MB, Simeonov A. Davis MI, et al. Among authors: fox jt. J Biol Chem. 2016 Nov 18;291(47):24628-24640. doi: 10.1074/jbc.M116.738567. Epub 2016 Sep 28. J Biol Chem. 2016. PMID: 27681596 Free PMC article.
The HIV protease inhibitor, ritonavir, corrects diverse brain phenotypes across development in mouse model of DYT-TOR1A dystonia.
Caffall ZF, Wilkes BJ, Hernández-Martinez R, Rittiner JE, Fox JT, Wan KK, Shipman MK, Titus SA, Zhang YQ, Patnaik S, Hall MD, Boxer MB, Shen M, Li Z, Vaillancourt DE, Calakos N. Caffall ZF, et al. Among authors: fox jt. Sci Transl Med. 2021 Aug 18;13(607):eabd3904. doi: 10.1126/scitranslmed.abd3904. Sci Transl Med. 2021. PMID: 34408078 Free PMC article.
Differential Effect of Non-Steroidal Anti-Inflammatory Drugs Aspirin and Naproxen against TMPRSS2-ERG (Fusion)-Driven and Non-Fusion-Driven Prostate Cancer.
Raina K, Kandhari K, Kant R, Prasad RR, Mishra N, Maurya AK, Fox JT, Sei S, Shoemaker RH, Bosland MC, Maroni P, Agarwal C, Agarwal R. Raina K, et al. Among authors: fox jt. Cancers (Basel). 2023 Oct 19;15(20):5054. doi: 10.3390/cancers15205054. Cancers (Basel). 2023. PMID: 37894421 Free PMC article.
Treatment Strategies and Mechanisms Associated with the Prevention of NASH-Associated HCC by a Toll-like Receptor 4 Inhibitor.
Kwan SY, Slayden AN, Coronado AR, Marquez RC, Chen H, Wei P, Savage MI, Vornik LA, Fox JT, Sei S, Liang D, Stevenson HL, Wilkerson GK, Gagea M, Brown PH, Beretta L. Kwan SY, et al. Among authors: fox jt. Cancer Prev Res (Phila). 2023 Jan 4;16(1):17-28. doi: 10.1158/1940-6207.CAPR-22-0332. Cancer Prev Res (Phila). 2023. PMID: 36162136 Free PMC article.
Oral administration of TRAIL-inducing small molecule ONC201/TIC10 prevents intestinal polyposis in the Apc min/+ mouse model.
Madka V, De La Cruz A, Pathuri G, Panneerselvam J, Zhang Y, Stratton N, Hacking S, Finnberg NK, Safran HP, Sei S, Glaze ER, Shoemaker R, Fox JT, Raufi AG, El-Deiry WS, Rao CV. Madka V, et al. Among authors: fox jt. Am J Cancer Res. 2022 May 15;12(5):2118-2131. eCollection 2022. Am J Cancer Res. 2022. PMID: 35693092 Free PMC article.
123 results