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Sialylation-dependent pharmacokinetics and differential complement pathway inhibition are hallmarks of CR1 activity in vivo.
Wymann S, Mischnik M, Leong D, Ghosh S, Tan X, Cao H, Kuehnemuth B, Powers GA, Halder P, de Souza MJ, James HS, Tomasetig V, Lind H, Rossato P, Owczarek CM, Ow SY, Dower SK, Baz Morelli A, Rowe T, Hardy MP. Wymann S, et al. Among authors: baz morelli a. Biochem J. 2022 May 13;479(9):1007-1030. doi: 10.1042/BCJ20220054. Biochem J. 2022. PMID: 35470373
A novel soluble complement receptor 1 fragment with enhanced therapeutic potential.
Wymann S, Dai Y, Nair AG, Cao H, Powers GA, Schnell A, Martin-Roussety G, Leong D, Simmonds J, Lieu KG, de Souza MJ, Mischnik M, Taylor S, Ow SY, Spycher M, Butcher RE, Pearse M, Zuercher AW, Baz Morelli A, Panousis C, Wilson MJ, Rowe T, Hardy MP. Wymann S, et al. Among authors: baz morelli a. J Biol Chem. 2021 Jan-Jun;296:100200. doi: 10.1074/jbc.RA120.016127. Epub 2020 Dec 23. J Biol Chem. 2021. PMID: 33334893 Free PMC article.
Immunization Strategies Producing a Humoral IgG Immune Response against Devil Facial Tumor Disease in the Majority of Tasmanian Devils Destined for Wild Release.
Pye R, Patchett A, McLennan E, Thomson R, Carver S, Fox S, Pemberton D, Kreiss A, Baz Morelli A, Silva A, Pearse MJ, Corcoran LM, Belov K, Hogg CJ, Woods GM, Lyons AB. Pye R, et al. Among authors: baz morelli a. Front Immunol. 2018 Feb 19;9:259. doi: 10.3389/fimmu.2018.00259. eCollection 2018. Front Immunol. 2018. PMID: 29515577 Free PMC article.
A Novel Cellular Pathway of Antigen Presentation and CD4 T Cell Activation in vivo.
Scales HE, Meehan GR, Hayes AJ, Benson RA, Watson E, Walters A, Tomura M, Maraskovsky E, Garside P, Baz Morelli A, Brewer JM. Scales HE, et al. Among authors: baz morelli a. Front Immunol. 2018 Nov 22;9:2684. doi: 10.3389/fimmu.2018.02684. eCollection 2018. Front Immunol. 2018. PMID: 30524434 Free PMC article.
rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and FcγRs.
Spirig R, Campbell IK, Koernig S, Chen CG, Lewis BJB, Butcher R, Muir I, Taylor S, Chia J, Leong D, Simmonds J, Scotney P, Schmidt P, Fabri L, Hofmann A, Jordi M, Spycher MO, Cattepoel S, Brasseit J, Panousis C, Rowe T, Branch DR, Baz Morelli A, Käsermann F, Zuercher AW. Spirig R, et al. Among authors: baz morelli a. J Immunol. 2018 Apr 15;200(8):2542-2553. doi: 10.4049/jimmunol.1701171. Epub 2018 Mar 12. J Immunol. 2018. PMID: 29531170 Free PMC article.
19 results