Denny WA - Search Results

1

Effect of common and experimental anti-tuberculosis treatments on Mycobacterium tuberculosis growing as biofilms.

Dalton JP, Uy B, Phummarin N, Copp BR, Denny WA, Swift S, Wiles S. Dalton JP, et al. Among authors: denny wa. PeerJ. 2016 Nov 22;4:e2717. doi: 10.7717/peerj.2717. eCollection 2016. PeerJ. 2016. PMID: 27904808 Free PMC article.

2

Screening of anti-mycobacterial compounds in a naturally infected zebrafish larvae model.

Dalton JP, Uy B, Okuda KS, Hall CJ, Denny WA, Crosier PS, Swift S, Wiles S. Dalton JP, et al. Among authors: denny wa. J Antimicrob Chemother. 2017 Feb;72(2):421-427. doi: 10.1093/jac/dkw421. Epub 2016 Oct 24. J Antimicrob Chemother. 2017. PMID: 27798206

3

Synthesis and anti-inflammatory structure-activity relationships of thiazine-quinoline-quinones: inhibitors of the neutrophil respiratory burst in a model of acute gouty arthritis.

Chia EW, Pearce AN, Berridge MV, Larsen L, Perry NB, Sansom CE, Godfrey CA, Hanton LR, Lu GL, Walton M, Denny WA, Webb VL, Copp BR, Harper JL. Chia EW, et al. Among authors: denny wa. Bioorg Med Chem. 2008 Nov 1;16(21):9432-42. doi: 10.1016/j.bmc.2008.09.052. Epub 2008 Sep 20. Bioorg Med Chem. 2008. PMID: 18835721

4

Synthesis and structure-activity relationships for tetrahydroisoquinoline-based inhibitors of Mycobacterium tuberculosis.

Lu GL, Tong AST, Conole D, Sutherland HS, Choi PJ, Franzblau SG, Upton AM, Lotlikar MU, Cooper CB, Denny WA, Palmer BD. Lu GL, et al. Among authors: denny wa. Bioorg Med Chem. 2020 Nov 15;28(22):115784. doi: 10.1016/j.bmc.2020.115784. Epub 2020 Sep 24. Bioorg Med Chem. 2020. PMID: 33007562 Free PMC article.

5

Structure-activity relationships for analogs of the tuberculosis drug bedaquiline with the naphthalene unit replaced by bicyclic heterocycles.

Sutherland HS, Tong AST, Choi PJ, Conole D, Blaser A, Franzblau SG, Cooper CB, Upton AM, Lotlikar MU, Denny WA, Palmer BD. Sutherland HS, et al. Among authors: denny wa. Bioorg Med Chem. 2018 May 1;26(8):1797-1809. doi: 10.1016/j.bmc.2018.02.026. Epub 2018 Feb 20. Bioorg Med Chem. 2018. PMID: 29482950 Free PMC article.

6

Synthesis and structure-activity relationships for a new class of tetrahydronaphthalene amide inhibitors of Mycobacterium tuberculosis.

Sutherland HS, Lu GL, Tong AST, Conole D, Franzblau SG, Upton AM, Lotlikar MU, Cooper CB, Palmer BD, Choi PJ, Denny WA. Sutherland HS, et al. Among authors: denny wa. Eur J Med Chem. 2022 Feb 5;229:114059. doi: 10.1016/j.ejmech.2021.114059. Epub 2021 Dec 21. Eur J Med Chem. 2022. PMID: 34963068 Free PMC article.

7

Synthesis and Structure-Activity Relationships for the Anti-Mycobacterial Activity of 3-Phenyl-N-(Pyridin-2-ylmethyl)Pyrazolo[1,5-a]Pyrimidin-7-Amines.

Sutherland HS, Choi PJ, Lu GL, Giddens AC, Tong AST, Franzblau SG, Cooper CB, Palmer BD, Denny WA. Sutherland HS, et al. Among authors: denny wa. Pharmaceuticals (Basel). 2022 Sep 8;15(9):1125. doi: 10.3390/ph15091125. Pharmaceuticals (Basel). 2022. PMID: 36145345 Free PMC article.

8

Comparative bioactivation of the novel anti-tuberculosis agent PA-824 in Mycobacteria and a subcellular fraction of human liver.

Dogra M, Palmer BD, Bashiri G, Tingle MD, Shinde SS, Anderson RF, O'Toole R, Baker EN, Denny WA, Helsby NA. Dogra M, et al. Among authors: denny wa. Br J Pharmacol. 2011 Jan;162(1):226-36. doi: 10.1111/j.1476-5381.2010.01040.x. Br J Pharmacol. 2011. PMID: 20955364 Free PMC article.

9

Inhibitors of F₁F₀-ATP synthase enzymes for the treatment of tuberculosis and cancer.

Denny WA. Denny WA. Future Med Chem. 2021 May;13(10):911-926. doi: 10.4155/fmc-2021-0010. Epub 2021 Apr 13. Future Med Chem. 2021. PMID: 33845594 Review.

10

Repurposing the chemical scaffold of the anti-arthritic drug Lobenzarit to target tryptophan biosynthesis in Mycobacterium tuberculosis.

Evans GL, Gamage SA, Bulloch EM, Baker EN, Denny WA, Lott JS. Evans GL, et al. Among authors: denny wa. Chembiochem. 2014 Apr 14;15(6):852-64. doi: 10.1002/cbic.201300628. Epub 2014 Mar 12. Chembiochem. 2014. PMID: 24623674

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