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Machine Learning based histology phenotyping to investigate the epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits.
Glastonbury CA, Pulit SL, Honecker J, Censin JC, Laber S, Yaghootkar H, Rahmioglu N, Pastel E, Kos K, Pitt A, Hudson M, Nellåker C, Beer NL, Hauner H, Becker CM, Zondervan KT, Frayling TM, Claussnitzer M, Lindgren CM. Glastonbury CA, et al. Among authors: kos k. PLoS Comput Biol. 2020 Aug 14;16(8):e1008044. doi: 10.1371/journal.pcbi.1008044. eCollection 2020 Aug. PLoS Comput Biol. 2020. PMID: 32797044 Free PMC article.
NK cell heparanase controls tumor invasion and immune surveillance.
Putz EM, Mayfosh AJ, Kos K, Barkauskas DS, Nakamura K, Town L, Goodall KJ, Yee DY, Poon IK, Baschuk N, Souza-Fonseca-Guimaraes F, Hulett MD, Smyth MJ. Putz EM, et al. Among authors: kos k. J Clin Invest. 2024 Jul 1;134(13):e183295. doi: 10.1172/JCI183295. J Clin Invest. 2024. PMID: 38949030 Free PMC article. No abstract available.
Neoadjuvant immune checkpoint blockade triggers persistent and systemic Treg activation which blunts therapeutic efficacy against metastatic spread of breast tumors.
Blomberg OS, Kos K, Spagnuolo L, Isaeva OI, Garner H, Wellenstein MD, Bakker N, Duits DEM, Kersten K, Klarenbeek S, Hau CS, Kaldenbach D, Raeven EAM, Vrijland K, Kok M, de Visser KE. Blomberg OS, et al. Among authors: kos k. Oncoimmunology. 2023 Apr 13;12(1):2201147. doi: 10.1080/2162402X.2023.2201147. eCollection 2023. Oncoimmunology. 2023. PMID: 37089449 Free PMC article.
IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer.
Blomberg OS, Spagnuolo L, Garner H, Voorwerk L, Isaeva OI, van Dyk E, Bakker N, Chalabi M, Klaver C, Duijst M, Kersten K, Brüggemann M, Pastoors D, Hau CS, Vrijland K, Raeven EAM, Kaldenbach D, Kos K, Afonina IS, Kaptein P, Hoes L, Theelen WSME, Baas P, Voest EE, Beyaert R, Thommen DS, Wessels LFA, de Visser KE, Kok M. Blomberg OS, et al. Among authors: kos k. Cancer Cell. 2023 Jan 9;41(1):106-123.e10. doi: 10.1016/j.ccell.2022.11.014. Epub 2022 Dec 15. Cancer Cell. 2023. PMID: 36525971 Free article.
Pro-mutagenic effects of the gut microbiota in a Lynch syndrome mouse model.
Pieters W, Hugenholtz F, Kos K, Cammeraat M, Moliej TC, Kaldenbach D, Klarenbeek S, Davids M, Drost L, de Konink C, Delzenne-Goette E, de Visser KE, Te Riele H. Pieters W, et al. Among authors: kos k. Gut Microbes. 2022 Jan-Dec;14(1):2035660. doi: 10.1080/19490976.2022.2035660. Gut Microbes. 2022. PMID: 35188867 Free PMC article.
91 results