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Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13Rα1 and IL-13Rα2.
Popovic B, Breed J, Rees DG, Gardener MJ, Vinall LM, Kemp B, Spooner J, Keen J, Minter R, Uddin F, Colice G, Wilkinson T, Vaughan T, May RD. Popovic B, et al. Among authors: keen j. J Mol Biol. 2017 Jan 20;429(2):208-219. doi: 10.1016/j.jmb.2016.12.005. Epub 2016 Dec 9. J Mol Biol. 2017. PMID: 27956146 Free article.
Engineering the expression of an anti-interleukin-13 antibody through rational design and mutagenesis.
Popovic B, Gibson S, Senussi T, Carmen S, Kidd S, Slidel T, Strickland I, Jianqing X, Spooner J, Lewis A, Hudson N, Mackenzie L, Keen J, Kemp B, Hardman C, Hatton D, Wilkinson T, Vaughan T, Lowe D. Popovic B, et al. Among authors: keen j. Protein Eng Des Sel. 2017 Apr 1;30(4):303-311. doi: 10.1093/protein/gzx001. Protein Eng Des Sel. 2017. PMID: 28130326
612 results