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Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors.
Huang X, Motea EA, Moore ZR, Yao J, Dong Y, Chakrabarti G, Kilgore JA, Silvers MA, Patidar PL, Cholka A, Fattah F, Cha Y, Anderson GG, Kusko R, Peyton M, Yan J, Xie XJ, Sarode V, Williams NS, Minna JD, Beg M, Gerber DE, Bey EA, Boothman DA. Huang X, et al. Among authors: cholka a. Cancer Cell. 2016 Dec 12;30(6):940-952. doi: 10.1016/j.ccell.2016.11.006. Cancer Cell. 2016. PMID: 27960087 Free PMC article.
Prolonged activation of innate immune pathways by a polyvalent STING agonist.
Li S, Luo M, Wang Z, Feng Q, Wilhelm J, Wang X, Li W, Wang J, Cholka A, Fu YX, Sumer BD, Yu H, Gao J. Li S, et al. Among authors: cholka a. Nat Biomed Eng. 2021 May;5(5):455-466. doi: 10.1038/s41551-020-00675-9. Epub 2021 Feb 8. Nat Biomed Eng. 2021. PMID: 33558734 Free PMC article.
Platelet ITAM signaling is critical for vascular integrity in inflammation.
Boulaftali Y, Hess PR, Getz TM, Cholka A, Stolla M, Mackman N, Owens AP 3rd, Ware J, Kahn ML, Bergmeier W. Boulaftali Y, et al. Among authors: cholka a. J Clin Invest. 2013 Feb;123(2):908-16. doi: 10.1172/JCI65154. Epub 2013 Jan 25. J Clin Invest. 2013. PMID: 23348738 Free PMC article.