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Combinational deletion of three membrane protein-encoding genes highly attenuates yersinia pestis while retaining immunogenicity in a mouse model of pneumonic plague.
Tiner BL, Sha J, Kirtley ML, Erova TE, Popov VL, Baze WB, van Lier CJ, Ponnusamy D, Andersson JA, Motin VL, Chauhan S, Chopra AK. Tiner BL, et al. Among authors: motin vl. Infect Immun. 2015 Apr;83(4):1318-38. doi: 10.1128/IAI.02778-14. Epub 2015 Jan 20. Infect Immun. 2015. PMID: 25605764 Free PMC article.
Characterization of an F1 deletion mutant of Yersinia pestis CO92, pathogenic role of F1 antigen in bubonic and pneumonic plague, and evaluation of sensitivity and specificity of F1 antigen capture-based dipsticks.
Sha J, Endsley JJ, Kirtley ML, Foltz SM, Huante MB, Erova TE, Kozlova EV, Popov VL, Yeager LA, Zudina IV, Motin VL, Peterson JW, DeBord KL, Chopra AK. Sha J, et al. Among authors: motin vl. J Clin Microbiol. 2011 May;49(5):1708-15. doi: 10.1128/JCM.00064-11. Epub 2011 Mar 2. J Clin Microbiol. 2011. PMID: 21367990 Free PMC article.
Evaluation of protective potential of Yersinia pestis outer membrane protein antigens as possible candidates for a new-generation recombinant plague vaccine.
Erova TE, Rosenzweig JA, Sha J, Suarez G, Sierra JC, Kirtley ML, van Lier CJ, Telepnev MV, Motin VL, Chopra AK. Erova TE, et al. Among authors: motin vl. Clin Vaccine Immunol. 2013 Feb;20(2):227-38. doi: 10.1128/CVI.00597-12. Epub 2012 Dec 12. Clin Vaccine Immunol. 2013. PMID: 23239803 Free PMC article.
Further characterization of a highly attenuated Yersinia pestis CO92 mutant deleted for the genes encoding Braun lipoprotein and plasminogen activator protease in murine alveolar and primary human macrophages.
van Lier CJ, Tiner BL, Chauhan S, Motin VL, Fitts EC, Huante MB, Endsley JJ, Ponnusamy D, Sha J, Chopra AK. van Lier CJ, et al. Among authors: motin vl. Microb Pathog. 2015 Mar;80:27-38. doi: 10.1016/j.micpath.2015.02.005. Epub 2015 Feb 16. Microb Pathog. 2015. PMID: 25697665 Free PMC article.
New Role for FDA-Approved Drugs in Combating Antibiotic-Resistant Bacteria.
Andersson JA, Fitts EC, Kirtley ML, Ponnusamy D, Peniche AG, Dann SM, Motin VL, Chauhan S, Rosenzweig JA, Sha J, Chopra AK. Andersson JA, et al. Among authors: motin vl. Antimicrob Agents Chemother. 2016 May 23;60(6):3717-29. doi: 10.1128/AAC.00326-16. Print 2016 Jun. Antimicrob Agents Chemother. 2016. PMID: 27067323 Free PMC article.
A Replication-Defective Human Type 5 Adenovirus-Based Trivalent Vaccine Confers Complete Protection against Plague in Mice and Nonhuman Primates.
Sha J, Kirtley ML, Klages C, Erova TE, Telepnev M, Ponnusamy D, Fitts EC, Baze WB, Sivasubramani SK, Lawrence WS, Patrikeev I, Peel JE, Andersson JA, Kozlova EV, Tiner BL, Peterson JW, McWilliams D, Patel S, Rothe E, Motin VL, Chopra AK. Sha J, et al. Among authors: motin vl. Clin Vaccine Immunol. 2016 Jul 5;23(7):586-600. doi: 10.1128/CVI.00150-16. Print 2016 Jul. Clin Vaccine Immunol. 2016. PMID: 27170642 Free PMC article.
77 results