Bublik DR - Search Results

1

Regulatory module involving FGF13, miR-504, and p53 regulates ribosomal biogenesis and supports cancer cell survival.

Bublik DR, Bursać S, Sheffer M, Oršolić I, Shalit T, Tarcic O, Kotler E, Mouhadeb O, Hoffman Y, Fuchs G, Levin Y, Volarević S, Oren M. Bublik DR, et al. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E496-E505. doi: 10.1073/pnas.1614876114. Epub 2016 Dec 19. Proc Natl Acad Sci U S A. 2017. PMID: 27994142 Free PMC article.

2

miR-661 downregulates both Mdm2 and Mdm4 to activate p53.

Hoffman Y, Bublik DR, Pilpel Y, Oren M. Hoffman Y, et al. Among authors: bublik dr. Cell Death Differ. 2014 Feb;21(2):302-9. doi: 10.1038/cdd.2013.146. Epub 2013 Oct 18. Cell Death Differ. 2014. PMID: 24141721 Free PMC article.

3

let-7b and let-7c microRNAs promote histone H2B ubiquitylation and inhibit cell migration by targeting multiple components of the H2B deubiquitylation machinery.

Spolverini A, Fuchs G, Bublik DR, Oren M. Spolverini A, et al. Among authors: bublik dr. Oncogene. 2017 Oct 19;36(42):5819-5828. doi: 10.1038/onc.2017.187. Epub 2017 Jun 12. Oncogene. 2017. PMID: 28604753 Free PMC article.

4

Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis.

Golomb L, Bublik DR, Wilder S, Nevo R, Kiss V, Grabusic K, Volarevic S, Oren M. Golomb L, et al. Among authors: bublik dr. Mol Cell. 2012 Jan 27;45(2):222-32. doi: 10.1016/j.molcel.2011.11.022. Mol Cell. 2012. PMID: 22284678 Free PMC article.

5

Get your fingers out of p53's way!

Bublik DR, Oren M. Bublik DR, et al. EMBO Rep. 2012 Apr 2;13(4):282-3. doi: 10.1038/embor.2012.33. EMBO Rep. 2012. PMID: 22422000 Free PMC article. No abstract available.

6

3'UTR Shortening Potentiates MicroRNA-Based Repression of Pro-differentiation Genes in Proliferating Human Cells.

Hoffman Y, Bublik DR, Ugalde AP, Elkon R, Biniashvili T, Agami R, Oren M, Pilpel Y. Hoffman Y, et al. Among authors: bublik dr. PLoS Genet. 2016 Feb 23;12(2):e1005879. doi: 10.1371/journal.pgen.1005879. eCollection 2016 Feb. PLoS Genet. 2016. PMID: 26908102 Free PMC article.

7

The majority of endogenous microRNA targets within Alu elements avoid the microRNA machinery.

Hoffman Y, Dahary D, Bublik DR, Oren M, Pilpel Y. Hoffman Y, et al. Among authors: bublik dr. Bioinformatics. 2013 Apr 1;29(7):894-902. doi: 10.1093/bioinformatics/btt044. Epub 2013 Jan 29. Bioinformatics. 2013. PMID: 23361327

8

Reactivation of epigenetically silenced miR-512 and miR-373 sensitizes lung cancer cells to cisplatin and restricts tumor growth.

Adi Harel S, Bossel Ben-Moshe N, Aylon Y, Bublik DR, Moskovits N, Toperoff G, Azaiza D, Biagoni F, Fuchs G, Wilder S, Hellman A, Blandino G, Domany E, Oren M. Adi Harel S, et al. Among authors: bublik dr. Cell Death Differ. 2015 Aug;22(8):1328-40. doi: 10.1038/cdd.2014.221. Epub 2015 Jan 16. Cell Death Differ. 2015. PMID: 25591738 Free PMC article.

9

PAX8 activates a p53-p21-dependent pro-proliferative effect in high grade serous ovarian carcinoma.

Ghannam-Shahbari D, Jacob E, Kakun RR, Wasserman T, Korsensky L, Sternfeld O, Kagan J, Bublik DR, Aviel-Ronen S, Levanon K, Sabo E, Larisch S, Oren M, Hershkovitz D, Perets R. Ghannam-Shahbari D, et al. Among authors: bublik dr. Oncogene. 2018 Apr;37(17):2213-2224. doi: 10.1038/s41388-017-0040-z. Epub 2018 Jan 30. Oncogene. 2018. PMID: 29379162

10

MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents.

Monte M, Simonatto M, Peche LY, Bublik DR, Gobessi S, Pierotti MA, Rodolfo M, Schneider C. Monte M, et al. Among authors: bublik dr. Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11160-5. doi: 10.1073/pnas.0510834103. Epub 2006 Jul 17. Proc Natl Acad Sci U S A. 2006. PMID: 16847267 Free PMC article.

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