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Regulatory module involving FGF13, miR-504, and p53 regulates ribosomal biogenesis and supports cancer cell survival.
Bublik DR, Bursać S, Sheffer M, Oršolić I, Shalit T, Tarcic O, Kotler E, Mouhadeb O, Hoffman Y, Fuchs G, Levin Y, Volarević S, Oren M. Bublik DR, et al. Among authors: sheffer m. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E496-E505. doi: 10.1073/pnas.1614876114. Epub 2016 Dec 19. Proc Natl Acad Sci U S A. 2017. PMID: 27994142 Free PMC article.
Rescue of embryonic stem cells from cellular transformation by proteomic stabilization of mutant p53 and conversion into WT conformation.
Rivlin N, Katz S, Doody M, Sheffer M, Horesh S, Molchadsky A, Koifman G, Shetzer Y, Goldfinger N, Rotter V, Geiger T. Rivlin N, et al. Among authors: sheffer m. Proc Natl Acad Sci U S A. 2014 May 13;111(19):7006-11. doi: 10.1073/pnas.1320428111. Epub 2014 Apr 28. Proc Natl Acad Sci U S A. 2014. PMID: 24778235 Free PMC article.
Pathway-based personalized analysis of cancer.
Drier Y, Sheffer M, Domany E. Drier Y, et al. Among authors: sheffer m. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6388-93. doi: 10.1073/pnas.1219651110. Epub 2013 Apr 1. Proc Natl Acad Sci U S A. 2013. PMID: 23547110 Free PMC article.
SILAC identifies LAD1 as a filamin-binding regulator of actin dynamics in response to EGF and a marker of aggressive breast tumors.
Roth L, Srivastava S, Lindzen M, Sas-Chen A, Sheffer M, Lauriola M, Enuka Y, Noronha A, Mancini M, Lavi S, Tarcic G, Pines G, Nevo N, Heyman O, Ziv T, Rueda OM, Gnocchi D, Pikarsky E, Admon A, Caldas C, Yarden Y. Roth L, et al. Among authors: sheffer m. Sci Signal. 2018 Jan 30;11(515):eaan0949. doi: 10.1126/scisignal.aan0949. Sci Signal. 2018. PMID: 29382783
Replication stress links structural and numerical cancer chromosomal instability.
Burrell RA, McClelland SE, Endesfelder D, Groth P, Weller MC, Shaikh N, Domingo E, Kanu N, Dewhurst SM, Gronroos E, Chew SK, Rowan AJ, Schenk A, Sheffer M, Howell M, Kschischo M, Behrens A, Helleday T, Bartek J, Tomlinson IP, Swanton C. Burrell RA, et al. Among authors: sheffer m. Nature. 2013 Feb 28;494(7438):492-496. doi: 10.1038/nature11935. Nature. 2013. PMID: 23446422 Free PMC article.
49 results