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Knocking out CD70 rescues CD70-specific nanoCAR T cells from antigen-induced exhaustion.
De Munter S, Buhl JL, De Cock L, Van Parys A, Daneels W, Pascal E, Deseins L, Ingels J, Goetgeluk G, Jansen H, Billiet L, Pille M, Van Duyse J, Bonte S, Vandamme N, Van Dorpe J, Offner F, Leclerq G, Taghon T, Depla E, Tavernier J, Kerre T, Drost J, Vandekerckhove B. De Munter S, et al. Among authors: billiet l. Cancer Immunol Res. 2024 Jun 14. doi: 10.1158/2326-6066.CIR-23-0677. Online ahead of print. Cancer Immunol Res. 2024. PMID: 38874582
Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum.
Ingels J, De Cock L, Stevens D, Mayer RL, Théry F, Sanchez GS, Vermijlen D, Weening K, De Smet S, Lootens N, Brusseel M, Verstraete T, Buyle J, Van Houtte E, Devreker P, Heyns K, De Munter S, Van Lint S, Goetgeluk G, Bonte S, Billiet L, Pille M, Jansen H, Pascal E, Deseins L, Vantomme L, Verdonckt M, Roelandt R, Eekhout T, Vandamme N, Leclercq G, Taghon T, Kerre T, Vanommeslaeghe F, Dhondt A, Ferdinande L, Van Dorpe J, Desender L, De Ryck F, Vermassen F, Surmont V, Impens F, Menten B, Vermaelen K, Vandekerckhove B. Ingels J, et al. Among authors: billiet l. Cell Rep Med. 2024 May 21;5(5):101516. doi: 10.1016/j.xcrm.2024.101516. Epub 2024 Apr 15. Cell Rep Med. 2024. PMID: 38626769 Free PMC article. Clinical Trial.
The Wiskott-Aldrich syndrome protein is required for positive selection during T-cell lineage differentiation.
Pille M, Avila J, Sanchez GS, Goetgeluk G, De Munter S, Jansen H, Billiet L, Weening K, Xue H, Bonte S, Ingels J, De Cock L, Pascal E, Deseins L, Kerre T, Taghon T, Leclercq G, Vermijlen D, Davis B, Vandekerckhove B. Pille M, et al. Among authors: billiet l. Front Immunol. 2023 Jun 7;14:1188099. doi: 10.3389/fimmu.2023.1188099. eCollection 2023. Front Immunol. 2023. PMID: 37350958 Free PMC article.
Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage.
Billiet L, De Cock L, Sanchez Sanchez G, Mayer RL, Goetgeluk G, De Munter S, Pille M, Ingels J, Jansen H, Weening K, Pascal E, Raes K, Bonte S, Kerre T, Vandamme N, Seurinck R, Roels J, Lavaert M, Van Nieuwerburgh F, Leclercq G, Taghon T, Impens F, Menten B, Vermijlen D, Vandekerckhove B. Billiet L, et al. J Exp Med. 2023 Jun 5;220(6):e20220942. doi: 10.1084/jem.20220942. Epub 2023 Mar 20. J Exp Med. 2023. PMID: 36939517 Free PMC article.
Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials.
Ingels J, De Cock L, Mayer RL, Devreker P, Weening K, Heyns K, Lootens N, De Smet S, Brusseel M, De Munter S, Pille M, Billiet L, Goetgeluk G, Bonte S, Jansen H, Lint SV, Leclercq G, Taghon T, Menten B, Vermaelen K, Impens F, Vandekerckhove B. Ingels J, et al. Among authors: billiet l. Cytotherapy. 2022 Feb;24(2):213-222. doi: 10.1016/j.jcyt.2021.08.005. Epub 2021 Oct 22. Cytotherapy. 2022. PMID: 34696961 Free article.
77 results