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Alterations in the brain adenosine metabolism cause behavioral and neurological impairment in ADA-deficient mice and patients.
Sauer AV, Hernandez RJ, Fumagalli F, Bianchi V, Poliani PL, Dallatomasina C, Riboni E, Politi LS, Tabucchi A, Carlucci F, Casiraghi M, Carriglio N, Cominelli M, Forcellini CA, Barzaghi F, Ferrua F, Minicucci F, Medaglini S, Leocani L, la Marca G, Notarangelo LD, Azzari C, Comi G, Baldoli C, Canale S, Sessa M, D'Adamo P, Aiuti A. Sauer AV, et al. Among authors: politi ls. Sci Rep. 2017 Jan 11;7:40136. doi: 10.1038/srep40136. Sci Rep. 2017. PMID: 28074903 Free PMC article.
Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis.
Mazzoleni S, Politi LS, Pala M, Cominelli M, Franzin A, Sergi Sergi L, Falini A, De Palma M, Bulfone A, Poliani PL, Galli R. Mazzoleni S, et al. Among authors: politi ls. Cancer Res. 2010 Oct 1;70(19):7500-13. doi: 10.1158/0008-5472.CAN-10-2353. Epub 2010 Sep 21. Cancer Res. 2010. PMID: 20858720 Free article.
Growth defects and impaired cognitive-behavioral abilities in mice with knockout for Eif4h, a gene located in the mouse homolog of the Williams-Beuren syndrome critical region.
Capossela S, Muzio L, Bertolo A, Bianchi V, Dati G, Chaabane L, Godi C, Politi LS, Biffo S, D'Adamo P, Mallamaci A, Pannese M. Capossela S, et al. Among authors: politi ls. Am J Pathol. 2012 Mar;180(3):1121-1135. doi: 10.1016/j.ajpath.2011.12.008. Epub 2012 Jan 9. Am J Pathol. 2012. PMID: 22234171 Free article.
Gene signatures associated with mouse postnatal hindbrain neural stem cells and medulloblastoma cancer stem cells identify novel molecular mediators and predict human medulloblastoma molecular classification.
Corno D, Pala M, Cominelli M, Cipelletti B, Leto K, Croci L, Barili V, Brandalise F, Melzi R, Di Gregorio A, Sergi LS, Politi LS, Piemonti L, Bulfone A, Rossi P, Rossi F, Consalez GG, Poliani PL, Galli R. Corno D, et al. Among authors: politi ls. Cancer Discov. 2012 Jun;2(6):554-68. doi: 10.1158/2159-8290.CD-11-0199. Epub 2012 May 3. Cancer Discov. 2012. PMID: 22628409 Free article.
The proneural gene ASCL1 governs the transcriptional subgroup affiliation in glioblastoma stem cells by directly repressing the mesenchymal gene NDRG1.
Narayanan A, Gagliardi F, Gallotti AL, Mazzoleni S, Cominelli M, Fagnocchi L, Pala M, Piras IS, Zordan P, Moretta N, Tratta E, Brugnara G, Altabella L, Bozzuto G, Gorombei P, Molinari A, Padua RA, Bulfone A, Politi LS, Falini A, Castellano A, Mortini P, Zippo A, Poliani PL, Galli R. Narayanan A, et al. Among authors: politi ls. Cell Death Differ. 2019 Sep;26(9):1813-1831. doi: 10.1038/s41418-018-0248-7. Epub 2018 Dec 11. Cell Death Differ. 2019. PMID: 30538287 Free PMC article.
Enhanced SPARCL1 expression in cancer stem cells improves preclinical modeling of glioblastoma by promoting both tumor infiltration and angiogenesis.
Gagliardi F, Narayanan A, Gallotti AL, Pieri V, Mazzoleni S, Cominelli M, Rezzola S, Corsini M, Brugnara G, Altabella L, Politi LS, Bacigaluppi M, Falini A, Castellano A, Ronca R, Poliani PL, Mortini P, Galli R. Gagliardi F, et al. Among authors: politi ls. Neurobiol Dis. 2020 Feb;134:104705. doi: 10.1016/j.nbd.2019.104705. Epub 2019 Dec 10. Neurobiol Dis. 2020. PMID: 31830525 Free article.
135 results