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Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma.
Falletta P, Sanchez-Del-Campo L, Chauhan J, Effern M, Kenyon A, Kershaw CJ, Siddaway R, Lisle R, Freter R, Daniels MJ, Lu X, Tüting T, Middleton M, Buffa FM, Willis AE, Pavitt G, Ronai ZA, Sauka-Spengler T, Hölzel M, Goding CR. Falletta P, et al. Among authors: willis ae. Genes Dev. 2017 Jan 1;31(1):18-33. doi: 10.1101/gad.290940.116. Epub 2017 Jan 17. Genes Dev. 2017. PMID: 28096186 Free PMC article.
A common polymorphism in the 5' UTR of ERCC5 creates an upstream ORF that confers resistance to platinum-based chemotherapy.
Somers J, Wilson LA, Kilday JP, Horvilleur E, Cannell IG, Pöyry TA, Cobbold LC, Kondrashov A, Knight JR, Puget S, Grill J, Grundy RG, Bushell M, Willis AE. Somers J, et al. Among authors: willis ae. Genes Dev. 2015 Sep 15;29(18):1891-6. doi: 10.1101/gad.261867.115. Epub 2015 Sep 3. Genes Dev. 2015. PMID: 26338418 Free PMC article.
Post-transcriptional control of stress responses in cancer.
Harvey RF, Willis AE. Harvey RF, et al. Among authors: willis ae. Curr Opin Genet Dev. 2018 Feb;48:30-35. doi: 10.1016/j.gde.2017.10.006. Epub 2017 Nov 5. Curr Opin Genet Dev. 2018. PMID: 29100210 Free article. Review.
Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes.
Powley IR, Kondrashov A, Young LA, Dobbyn HC, Hill K, Cannell IG, Stoneley M, Kong YW, Cotes JA, Smith GC, Wek R, Hayes C, Gant TW, Spriggs KA, Bushell M, Willis AE. Powley IR, et al. Among authors: willis ae. Genes Dev. 2009 May 15;23(10):1207-20. doi: 10.1101/gad.516509. Genes Dev. 2009. PMID: 19451221 Free PMC article.
Translation deregulation in B-cell lymphomas.
Horvilleur E, Wilson LA, Willis AE. Horvilleur E, et al. Among authors: willis ae. Biochem Soc Trans. 2010 Dec;38(6):1593-7. doi: 10.1042/BST0381593. Biochem Soc Trans. 2010. PMID: 21118132
Engagement of the B-cell receptor of chronic lymphocytic leukemia cells drives global and MYC-specific mRNA translation.
Yeomans A, Thirdborough SM, Valle-Argos B, Linley A, Krysov S, Hidalgo MS, Leonard E, Ishfaq M, Wagner SD, Willis AE, Steele AJ, Stevenson FK, Forconi F, Coldwell MJ, Packham G. Yeomans A, et al. Among authors: willis ae. Blood. 2016 Jan 28;127(4):449-57. doi: 10.1182/blood-2015-07-660969. Epub 2015 Oct 21. Blood. 2016. PMID: 26491071 Free article.
Cap-Independent Translation in Hematological Malignancies.
Horvilleur E, Wilson LA, Bastide A, Piñeiro D, Pöyry TA, Willis AE. Horvilleur E, et al. Among authors: willis ae. Front Oncol. 2015 Dec 21;5:293. doi: 10.3389/fonc.2015.00293. eCollection 2015. Front Oncol. 2015. PMID: 26734574 Free PMC article. Review.
173 results