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Targeting Alpha Toxin To Mitigate Its Lethal Toxicity in Ferret and Rabbit Models of Staphylococcus aureus Necrotizing Pneumonia.
Diep BA, Hilliard JJ, Le VT, Tkaczyk C, Le HN, Tran VG, Rao RL, Dip EC, Pereira-Franchi EP, Cha P, Jacobson S, Broome R, Cheng LI, Weiss W, Prokai L, Nguyen V, Stover CK, Sellman BR. Diep BA, et al. Among authors: le vt, le hn. Antimicrob Agents Chemother. 2017 Mar 24;61(4):e02456-16. doi: 10.1128/AAC.02456-16. Print 2017 Apr. Antimicrob Agents Chemother. 2017. PMID: 28115346 Free PMC article.
Staphylococcus aureus α toxin potentiates opportunistic bacterial lung infections.
Cohen TS, Hilliard JJ, Jones-Nelson O, Keller AE, O'Day T, Tkaczyk C, DiGiandomenico A, Hamilton M, Pelletier M, Wang Q, Diep BA, Le VT, Cheng L, Suzich J, Stover CK, Sellman BR. Cohen TS, et al. Among authors: le vt. Sci Transl Med. 2016 Mar 9;8(329):329ra31. doi: 10.1126/scitranslmed.aad9922. Sci Transl Med. 2016. PMID: 26962155
Critical Role of Alpha-Toxin and Protective Effects of Its Neutralization by a Human Antibody in Acute Bacterial Skin and Skin Structure Infections.
Le VT, Tkaczyk C, Chau S, Rao RL, Dip EC, Pereira-Franchi EP, Cheng L, Lee S, Koelkebeck H, Hilliard JJ, Yu XQ, Datta V, Nguyen V, Weiss W, Prokai L, O'Day T, Stover CK, Sellman BR, Diep BA. Le VT, et al. Antimicrob Agents Chemother. 2016 Sep 23;60(10):5640-8. doi: 10.1128/AAC.00710-16. Print 2016 Oct. Antimicrob Agents Chemother. 2016. PMID: 27401576 Free PMC article.
Improved Protection in a Rabbit Model of Community-Associated Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia upon Neutralization of Leukocidins in Addition to Alpha-Hemolysin.
Diep BA, Le VT, Visram ZC, Rouha H, Stulik L, Dip EC, Nagy G, Nagy E. Diep BA, et al. Among authors: le vt. Antimicrob Agents Chemother. 2016 Sep 23;60(10):6333-40. doi: 10.1128/AAC.01213-16. Print 2016 Oct. Antimicrob Agents Chemother. 2016. PMID: 27527081 Free PMC article.
IVIG-mediated protection against necrotizing pneumonia caused by MRSA.
Diep BA, Le VT, Badiou C, Le HN, Pinheiro MG, Duong AH, Wang X, Dip EC, Aguiar-Alves F, Basuino L, Marbach H, Mai TT, Sarda MN, Kajikawa O, Matute-Bello G, Tkaczyk C, Rasigade JP, Sellman BR, Chambers HF, Lina G. Diep BA, et al. Among authors: le vt, le hn. Sci Transl Med. 2016 Sep 21;8(357):357ra124. doi: 10.1126/scitranslmed.aag1153. Sci Transl Med. 2016. PMID: 27655850
Effects of Tedizolid Phosphate on Survival Outcomes and Suppression of Production of Staphylococcal Toxins in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia.
Le VT, Le HN, Pinheiro MG, Hahn KJ, Dinh ML, Larson KB, Flanagan SD, Badiou C, Lina G, Tkaczyk C, Sellman BR, Diep BA. Le VT, et al. Among authors: le hn. Antimicrob Agents Chemother. 2017 Mar 24;61(4):e02734-16. doi: 10.1128/AAC.02734-16. Print 2017 Apr. Antimicrob Agents Chemother. 2017. PMID: 28137816 Free PMC article.
Delta Hemolysin and Phenol-Soluble Modulins, but Not Alpha Hemolysin or Panton-Valentine Leukocidin, Induce Mast Cell Activation.
Hodille E, Cuerq C, Badiou C, Bienvenu F, Steghens JP, Cartier R, Bes M, Tristan A, Plesa A, Le VT, Diep BA, Lina G, Dumitrescu O. Hodille E, et al. Among authors: le vt. Front Cell Infect Microbiol. 2016 Dec 12;6:180. doi: 10.3389/fcimb.2016.00180. eCollection 2016. Front Cell Infect Microbiol. 2016. PMID: 28018862 Free PMC article.
248 results