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EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells.
Oncotarget. 2017 Apr 11;8(15):24679-24693. doi: 10.18632/oncotarget.14976.
Oncotarget. 2017.
PMID: 28160567
Free PMC article.
Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers.
Tsafou K, Katschnig AM, Radic-Sarikas B, Mutz CN, Iljin K, Schwentner R, Kauer MO, Mühlbacher K, Aryee DNT, Westergaard D, Haapa-Paananen S, Fey V, Superti-Furga G, Toretsky J, Brunak S, Kovar H.
Tsafou K, et al. Among authors: mutz cn.
Oncotarget. 2018 Jul 24;9(57):31018-31031. doi: 10.18632/oncotarget.25760. eCollection 2018 Jul 24.
Oncotarget. 2018.
PMID: 30123424
Free PMC article.
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EWS-FLI1 perturbs MRTFB/YAP-1/TEAD target gene regulation inhibiting cytoskeletal autoregulatory feedback in Ewing sarcoma.
Katschnig AM, Kauer MO, Schwentner R, Tomazou EM, Mutz CN, Linder M, Sibilia M, Alonso J, Aryee DNT, Kovar H.
Katschnig AM, et al. Among authors: mutz cn.
Oncogene. 2017 Oct 26;36(43):5995-6005. doi: 10.1038/onc.2017.202. Epub 2017 Jul 3.
Oncogene. 2017.
PMID: 28671673
Free PMC article.
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EWS-FLI1 impairs aryl hydrocarbon receptor activation by blocking tryptophan breakdown via the kynurenine pathway.
Mutz CN, Schwentner R, Kauer MO, Katschnig AM, Kromp F, Aryee DN, Erhardt S, Goiny M, Alonso J, Fuchs D, Kovar H.
Mutz CN, et al.
FEBS Lett. 2016 Jul;590(14):2063-75. doi: 10.1002/1873-3468.12243. Epub 2016 Jun 21.
FEBS Lett. 2016.
PMID: 27282934
Free PMC article.
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The role of miR-17-92 in the miRegulatory landscape of Ewing sarcoma.
Schwentner R, Herrero-Martin D, Kauer MO, Mutz CN, Katschnig AM, Sienski G, Alonso J, Aryee DN, Kovar H.
Schwentner R, et al. Among authors: mutz cn.
Oncotarget. 2017 Feb 14;8(7):10980-10993. doi: 10.18632/oncotarget.14091.
Oncotarget. 2017.
PMID: 28030800
Free PMC article.
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Combinatorial Drug Screening Identifies Ewing Sarcoma-specific Sensitivities.
Radic-Sarikas B, Tsafou KP, Emdal KB, Papamarkou T, Huber KV, Mutz C, Toretsky JA, Bennett KL, Olsen JV, Brunak S, Kovar H, Superti-Furga G.
Radic-Sarikas B, et al.
Mol Cancer Ther. 2017 Jan;16(1):88-101. doi: 10.1158/1535-7163.MCT-16-0235. Epub 2016 Nov 15.
Mol Cancer Ther. 2017.
PMID: 28062706
Free article.
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