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PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier.
Pichery M, Huchenq A, Sandhoff R, Severino-Freire M, Zaafouri S, Opálka L, Levade T, Soldan V, Bertrand-Michel J, Lhuillier E, Serre G, Maruani A, Mazereeuw-Hautier J, Jonca N. Pichery M, et al. Hum Mol Genet. 2017 May 15;26(10):1787-1800. doi: 10.1093/hmg/ddx079. Hum Mol Genet. 2017. PMID: 28369476
Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target.
Smati S, Polizzi A, Fougerat A, Ellero-Simatos S, Blum Y, Lippi Y, Régnier M, Laroyenne A, Huillet M, Arif M, Zhang C, Lasserre F, Marrot A, Al Saati T, Wan J, Sommer C, Naylies C, Batut A, Lukowicz C, Fougeray T, Tramunt B, Dubot P, Smith L, Bertrand-Michel J, Hennuyer N, Pradere JP, Staels B, Burcelin R, Lenfant F, Arnal JF, Levade T, Gamet-Payrastre L, Lagarrigue S, Loiseau N, Lotersztajn S, Postic C, Wahli W, Bureau C, Guillaume M, Mardinoglu A, Montagner A, Gourdy P, Guillou H. Smati S, et al. Gut. 2022 Apr;71(4):807-821. doi: 10.1136/gutjnl-2020-323323. Epub 2021 Apr 26. Gut. 2022. PMID: 33903148 Free article.
The ω6-fatty acid, arachidonic acid, regulates the conversion of white to brite adipocyte through a prostaglandin/calcium mediated pathway.
Pisani DF, Ghandour RA, Beranger GE, Le Faouder P, Chambard JC, Giroud M, Vegiopoulos A, Djedaini M, Bertrand-Michel J, Tauc M, Herzig S, Langin D, Ailhaud G, Duranton C, Amri EZ. Pisani DF, et al. Mol Metab. 2014 Sep 16;3(9):834-47. doi: 10.1016/j.molmet.2014.09.003. eCollection 2014 Dec. Mol Metab. 2014. PMID: 25506549 Free PMC article.
Insights into the role of hepatocyte PPARα activity in response to fasting.
Régnier M, Polizzi A, Lippi Y, Fouché E, Michel G, Lukowicz C, Smati S, Marrot A, Lasserre F, Naylies C, Batut A, Viars F, Bertrand-Michel J, Postic C, Loiseau N, Wahli W, Guillou H, Montagner A. Régnier M, et al. Mol Cell Endocrinol. 2018 Aug 15;471:75-88. doi: 10.1016/j.mce.2017.07.035. Epub 2017 Jul 31. Mol Cell Endocrinol. 2018. PMID: 28774777
Analysis of Oxysterols.
Riols F, Bertrand-Michel J. Riols F, et al. Methods Mol Biol. 2018;1730:267-275. doi: 10.1007/978-1-4939-7592-1_19. Methods Mol Biol. 2018. PMID: 29363080
Profiling of phosphoinositide molecular species in human and mouse platelets identifies new species increasing following stimulation.
Mujalli A, Chicanne G, Bertrand-Michel J, Viars F, Stephens L, Hawkins P, Viaud J, Gaits-Iacovoni F, Severin S, Gratacap MP, Terrisse AD, Payrastre B. Mujalli A, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Sep;1863(9):1121-1131. doi: 10.1016/j.bbalip.2018.06.009. Epub 2018 Jun 12. Biochim Biophys Acta Mol Cell Biol Lipids. 2018. PMID: 29902570
134 results