Silke J - Search Results

1

Engineered Exosomes as Vehicles for Biologically Active Proteins.

Sterzenbach U, Putz U, Low LH, Silke J, Tan SS, Howitt J. Sterzenbach U, et al. Among authors: silke j. Mol Ther. 2017 Jun 7;25(6):1269-1278. doi: 10.1016/j.ymthe.2017.03.030. Epub 2017 Apr 13. Mol Ther. 2017. PMID: 28412169 Free PMC article.

2

Nedd4-WW domain-binding protein 5 (Ndfip1) is associated with neuronal survival after acute cortical brain injury.

Sang Q, Kim MH, Kumar S, Bye N, Morganti-Kossman MC, Gunnersen J, Fuller S, Howitt J, Hyde L, Beissbarth T, Scott HS, Silke J, Tan SS. Sang Q, et al. Among authors: silke j. J Neurosci. 2006 Jul 5;26(27):7234-44. doi: 10.1523/JNEUROSCI.1398-06.2006. J Neurosci. 2006. PMID: 16822981 Free PMC article.

3

Nedd4 family-interacting protein 1 (Ndfip1) is required for the exosomal secretion of Nedd4 family proteins.

Putz U, Howitt J, Lackovic J, Foot N, Kumar S, Silke J, Tan SS. Putz U, et al. Among authors: silke j. J Biol Chem. 2008 Nov 21;283(47):32621-7. doi: 10.1074/jbc.M804120200. Epub 2008 Sep 25. J Biol Chem. 2008. PMID: 18819914 Free article.

4

Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons.

Howitt J, Putz U, Lackovic J, Doan A, Dorstyn L, Cheng H, Yang B, Chan-Ling T, Silke J, Kumar S, Tan SS. Howitt J, et al. Among authors: silke j. Proc Natl Acad Sci U S A. 2009 Sep 8;106(36):15489-94. doi: 10.1073/pnas.0904880106. Epub 2009 Aug 25. Proc Natl Acad Sci U S A. 2009. PMID: 19706893 Free PMC article.

5

Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia.

Howitt J, Lackovic J, Low LH, Naguib A, Macintyre A, Goh CP, Callaway JK, Hammond V, Thomas T, Dixon M, Putz U, Silke J, Bartlett P, Yang B, Kumar S, Trotman LC, Tan SS. Howitt J, et al. Among authors: silke j. J Cell Biol. 2012 Jan 9;196(1):29-36. doi: 10.1083/jcb.201105009. Epub 2012 Jan 2. J Cell Biol. 2012. PMID: 22213801 Free PMC article.

6

Differential regulation of Nedd4 ubiquitin ligases and their adaptor protein Ndfip1 in a rat model of ischemic stroke.

Lackovic J, Howitt J, Callaway JK, Silke J, Bartlett P, Tan SS. Lackovic J, et al. Among authors: silke j. Exp Neurol. 2012 May;235(1):326-35. doi: 10.1016/j.expneurol.2012.02.014. Epub 2012 Mar 5. Exp Neurol. 2012. PMID: 22417925

7

The tumor suppressor PTEN is exported in exosomes and has phosphatase activity in recipient cells.

Putz U, Howitt J, Doan A, Goh CP, Low LH, Silke J, Tan SS. Putz U, et al. Among authors: silke j. Sci Signal. 2012 Sep 25;5(243):ra70. doi: 10.1126/scisignal.2003084. Sci Signal. 2012. PMID: 23012657

8

Nedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage response.

Low LH, Chow YL, Li Y, Goh CP, Putz U, Silke J, Ouchi T, Howitt J, Tan SS. Low LH, et al. Among authors: silke j. J Biol Chem. 2015 Mar 13;290(11):7141-50. doi: 10.1074/jbc.M114.613687. Epub 2015 Jan 28. J Biol Chem. 2015. PMID: 25631046 Free PMC article.

9

Ndfip1 represses cell proliferation by controlling Pten localization and signaling specificity.

Howitt J, Low LH, Putz U, Doan A, Lackovic J, Goh CP, Gunnersen J, Silke J, Tan SS. Howitt J, et al. Among authors: silke j. J Mol Cell Biol. 2015 Apr;7(2):119-31. doi: 10.1093/jmcb/mjv020. Epub 2015 Mar 23. J Mol Cell Biol. 2015. PMID: 25801959

10

Oligomerization-driven MLKL ubiquitylation antagonizes necroptosis.

Liu Z, Dagley LF, Shield-Artin K, Young SN, Bankovacki A, Wang X, Tang M, Howitt J, Stafford CA, Nachbur U, Fitzgibbon C, Garnish SE, Webb AI, Komander D, Murphy JM, Hildebrand JM, Silke J. Liu Z, et al. Among authors: silke j. EMBO J. 2021 Dec 1;40(23):e103718. doi: 10.15252/embj.2019103718. Epub 2021 Oct 26. EMBO J. 2021. PMID: 34698396 Free PMC article.

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