Letai A - Search Results

1

Epstein-Barr virus ensures B cell survival by uniquely modulating apoptosis at early and late times after infection.

Price AM, Dai J, Bazot Q, Patel L, Nikitin PA, Djavadian R, Winter PS, Salinas CA, Barry AP, Wood KC, Johannsen EC, Letai A, Allday MJ, Luftig MA. Price AM, et al. Among authors: letai a. Elife. 2017 Apr 20;6:e22509. doi: 10.7554/eLife.22509. Elife. 2017. PMID: 28425914 Free PMC article.

2

BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response.

Sarosiek KA, Chi X, Bachman JA, Sims JJ, Montero J, Patel L, Flanagan A, Andrews DW, Sorger P, Letai A. Sarosiek KA, et al. Among authors: letai a. Mol Cell. 2013 Sep 26;51(6):751-65. doi: 10.1016/j.molcel.2013.08.048. Mol Cell. 2013. PMID: 24074954 Free PMC article.

3

RAS signaling promotes resistance to JAK inhibitors by suppressing BAD-mediated apoptosis.

Winter PS, Sarosiek KA, Lin KH, Meggendorfer M, Schnittger S, Letai A, Wood KC. Winter PS, et al. Among authors: letai a. Sci Signal. 2014 Dec 23;7(357):ra122. doi: 10.1126/scisignal.2005301. Sci Signal. 2014. PMID: 25538080 Free PMC article.

4

To Prime, or Not to Prime: That Is the Question.

Potter DS, Letai A. Potter DS, et al. Among authors: letai a. Cold Spring Harb Symp Quant Biol. 2016;81:131-140. doi: 10.1101/sqb.2016.81.030841. Epub 2016 Nov 3. Cold Spring Harb Symp Quant Biol. 2016. PMID: 27811212 Review.

5

Synergistic interactions with PI3K inhibition that induce apoptosis.

Zwang Y, Jonas O, Chen C, Rinne ML, Doench JG, Piccioni F, Tan L, Huang HT, Wang J, Ham YJ, O'Connell J, Bhola P, Doshi M, Whitman M, Cima M, Letai A, Root DE, Langer RS, Gray N, Hahn WC. Zwang Y, et al. Among authors: letai a. Elife. 2017 May 31;6:e24523. doi: 10.7554/eLife.24523. Elife. 2017. PMID: 28561737 Free PMC article.

6

Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1.

Jenson JM, Ryan JA, Grant RA, Letai A, Keating AE. Jenson JM, et al. Among authors: letai a. Elife. 2017 Jun 8;6:e25541. doi: 10.7554/eLife.25541. Elife. 2017. PMID: 28594323 Free PMC article.

7

BH3 domains as BCL-2 inhibitors: prototype cancer therapeutics.

Letai A. Letai A. Expert Opin Biol Ther. 2003 Apr;3(2):293-304. doi: 10.1517/14712598.3.2.293. Expert Opin Biol Ther. 2003. PMID: 12662143

8

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

Opferman JT, Letai A, Beard C, Sorcinelli MD, Ong CC, Korsmeyer SJ. Opferman JT, et al. Among authors: letai a. Nature. 2003 Dec 11;426(6967):671-6. doi: 10.1038/nature02067. Nature. 2003. PMID: 14668867 Free article.

9

Growth factor withdrawal and apoptosis: the middle game.

Letai A. Letai A. Mol Cell. 2006 Mar 17;21(6):728-30. doi: 10.1016/j.molcel.2006.03.005. Mol Cell. 2006. PMID: 16543140 Free article. Review.

10

Restoring cancer's death sentence.

Letai A. Letai A. Cancer Cell. 2006 Nov;10(5):343-5. doi: 10.1016/j.ccr.2006.10.014. Cancer Cell. 2006. PMID: 17097553 Free article.

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