Tomašič T - Search Results

1

Xanthine oxidase inhibitors beyond allopurinol and febuxostat; an overview and selection of potential leads based on in silico calculated physico-chemical properties, predicted pharmacokinetics and toxicity.

Šmelcerović A, Tomović K, Šmelcerović Ž, Petronijević Ž, Kocić G, Tomašič T, Jakopin Ž, Anderluh M. Šmelcerović A, et al. Among authors: tomasic t. Eur J Med Chem. 2017 Jul 28;135:491-516. doi: 10.1016/j.ejmech.2017.04.031. Epub 2017 Apr 19. Eur J Med Chem. 2017. PMID: 28478180 Review.

2

Refined high-content imaging-based phenotypic drug screening in zebrafish xenografts.

Sturtzel C, Grissenberger S, Bozatzi P, Scheuringer E, Wenninger-Weinzierl A, Zajec Z, Dernovšek J, Pascoal S, Gehl V, Kutsch A, Granig A, Rifatbegovic F, Carre M, Lang A, Valtingojer I, Moll J, Lötsch D, Erhart F, Widhalm G, Surdez D, Delattre O, André N, Stampfl J, Tomašič T, Taschner-Mandl S, Distel M. Sturtzel C, et al. Among authors: tomasic t. NPJ Precis Oncol. 2023 May 18;7(1):44. doi: 10.1038/s41698-023-00386-9. NPJ Precis Oncol. 2023. PMID: 37202469 Free PMC article. Review.

3

Novel potent and selective thrombin inhibitors based on a central 1,4-benzoxazin-3(4H)-one scaffold.

Ilas J, Tomasić T, Kikelj D. Ilas J, et al. Among authors: tomasic t. J Med Chem. 2008 May 8;51(9):2863-7. doi: 10.1021/jm701622y. Epub 2008 Apr 16. J Med Chem. 2008. PMID: 18412326

4

Synthesis and biological evaluation of new glutamic acid-based inhibitors of MurD ligase.

Tomasić T, Zidar N, Rupnik V, Kovac A, Blanot D, Gobec S, Kikelj D, Masic LP. Tomasić T, et al. Bioorg Med Chem Lett. 2009 Jan 1;19(1):153-7. doi: 10.1016/j.bmcl.2008.10.129. Epub 2008 Nov 5. Bioorg Med Chem Lett. 2009. PMID: 19014883

5

Rhodanine as a privileged scaffold in drug discovery.

Tomasić T, Masic LP. Tomasić T, et al. Curr Med Chem. 2009;16(13):1596-629. doi: 10.2174/092986709788186200. Curr Med Chem. 2009. PMID: 19442136 Review.

6

5-Benzylidenethiazolidin-4-ones as multitarget inhibitors of bacterial Mur ligases.

Tomasić T, Zidar N, Kovac A, Turk S, Simcic M, Blanot D, Müller-Premru M, Filipic M, Grdadolnik SG, Zega A, Anderluh M, Gobec S, Kikelj D, Peterlin Masic L. Tomasić T, et al. ChemMedChem. 2010 Feb 1;5(2):286-95. doi: 10.1002/cmdc.200900449. ChemMedChem. 2010. PMID: 20024979

7

Synthesis and antibacterial activity of 5-ylidenethiazolidin-4-ones and 5-benzylidene-4,6-pyrimidinediones.

Tomasić T, Zidar N, Mueller-Premru M, Kikelj D, Masic LP. Tomasić T, et al. Eur J Med Chem. 2010 Apr;45(4):1667-72. doi: 10.1016/j.ejmech.2009.12.030. Epub 2009 Dec 22. Eur J Med Chem. 2010. PMID: 20060624

8

Discovery of novel 5-benzylidenerhodanine and 5-benzylidenethiazolidine-2,4-dione inhibitors of MurD ligase.

Zidar N, Tomasić T, Sink R, Rupnik V, Kovac A, Turk S, Patin D, Blanot D, Contreras Martel C, Dessen A, Müller Premru M, Zega A, Gobec S, Peterlin Masic L, Kikelj D. Zidar N, et al. Among authors: tomasic t. J Med Chem. 2010 Sep 23;53(18):6584-94. doi: 10.1021/jm100285g. J Med Chem. 2010. PMID: 20804196

9

ATP-binding site of bacterial enzymes as a target for antibacterial drug design.

Škedelj V, Tomašić T, Mašič LP, Zega A. Škedelj V, et al. Among authors: tomasic t. J Med Chem. 2011 Feb 24;54(4):915-29. doi: 10.1021/jm101121s. Epub 2011 Jan 14. J Med Chem. 2011. PMID: 21235241 Review. No abstract available.

10

Structure-based design of a new series of D-glutamic acid based inhibitors of bacterial UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (MurD).

Tomasić T, Zidar N, Sink R, Kovac A, Blanot D, Contreras-Martel C, Dessen A, Müller-Premru M, Zega A, Gobec S, Kikelj D, Masic LP. Tomasić T, et al. J Med Chem. 2011 Jul 14;54(13):4600-10. doi: 10.1021/jm2002525. Epub 2011 Jun 3. J Med Chem. 2011. PMID: 21591605

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