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The mitochondrial dynamics in cancer and immune-surveillance.
Simula L, Nazio F, Campello S. Simula L, et al. Among authors: campello s. Semin Cancer Biol. 2017 Dec;47:29-42. doi: 10.1016/j.semcancer.2017.06.007. Epub 2017 Jun 24. Semin Cancer Biol. 2017. PMID: 28655520 Review.
AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity.
Maiani E, Milletti G, Nazio F, Holdgaard SG, Bartkova J, Rizza S, Cianfanelli V, Lorente M, Simoneschi D, Di Marco M, D'Acunzo P, Di Leo L, Rasmussen R, Montagna C, Raciti M, De Stefanis C, Gabicagogeascoa E, Rona G, Salvador N, Pupo E, Merchut-Maya JM, Daniel CJ, Carinci M, Cesarini V, O'sullivan A, Jeong YT, Bordi M, Russo F, Campello S, Gallo A, Filomeni G, Lanzetti L, Sears RC, Hamerlik P, Bartolazzi A, Hynds RE, Pearce DR, Swanton C, Pagano M, Velasco G, Papaleo E, De Zio D, Maya-Mendoza A, Locatelli F, Bartek J, Cecconi F. Maiani E, et al. Among authors: campello s. Nature. 2021 Apr;592(7856):799-803. doi: 10.1038/s41586-021-03422-5. Epub 2021 Apr 14. Nature. 2021. PMID: 33854232 Free PMC article.
S-nitrosylation drives cell senescence and aging in mammals by controlling mitochondrial dynamics and mitophagy.
Rizza S, Cardaci S, Montagna C, Di Giacomo G, De Zio D, Bordi M, Maiani E, Campello S, Borreca A, Puca AA, Stamler JS, Cecconi F, Filomeni G. Rizza S, et al. Among authors: campello s. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3388-E3397. doi: 10.1073/pnas.1722452115. Epub 2018 Mar 26. Proc Natl Acad Sci U S A. 2018. PMID: 29581312 Free PMC article.
AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1.
Strappazzon F, Nazio F, Corrado M, Cianfanelli V, Romagnoli A, Fimia GM, Campello S, Nardacci R, Piacentini M, Campanella M, Cecconi F. Strappazzon F, et al. Among authors: campello s. Cell Death Differ. 2015 Mar;22(3):419-32. doi: 10.1038/cdd.2014.139. Epub 2014 Sep 12. Cell Death Differ. 2015. PMID: 25215947 Free PMC article.
Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T Cell Migration, Proliferation, and cMyc-Dependent Metabolic Reprogramming.
Simula L, Pacella I, Colamatteo A, Procaccini C, Cancila V, Bordi M, Tregnago C, Corrado M, Pigazzi M, Barnaba V, Tripodo C, Matarese G, Piconese S, Campello S. Simula L, et al. Among authors: campello s. Cell Rep. 2018 Dec 11;25(11):3059-3073.e10. doi: 10.1016/j.celrep.2018.11.018. Cell Rep. 2018. PMID: 30540939 Free PMC article.
Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling.
Nazio F, Po A, Abballe L, Ballabio C, Diomedi Camassei F, Bordi M, Camera A, Caruso S, Caruana I, Pezzullo M, Ferraina C, Milletti G, Gianesello M, Reddel S, De Luca CD, Ceglie D, Marinelli S, Campello S, Papaleo E, Miele E, Cacchione A, Carai A, Vinci M, Velardi E, De Angelis B, Tiberi L, Quintarelli C, Mastronuzzi A, Ferretti E, Locatelli F, Cecconi F. Nazio F, et al. Among authors: campello s. Acta Neuropathol. 2021 Sep;142(3):537-564. doi: 10.1007/s00401-021-02347-7. Epub 2021 Jul 24. Acta Neuropathol. 2021. PMID: 34302498 Free PMC article.
The long non-coding RNA CDK6-AS1 overexpression impacts on acute myeloid leukemia differentiation and mitochondrial dynamics.
Porcù E, Benetton M, Bisio V, Da Ros A, Tregnago C, Borella G, Zanon C, Bordi M, Germano G, Manni S, Campello S, Rao DS, Locatelli F, Pigazzi M. Porcù E, et al. Among authors: campello s. iScience. 2021 Oct 26;24(11):103350. doi: 10.1016/j.isci.2021.103350. eCollection 2021 Nov 19. iScience. 2021. PMID: 34816103 Free PMC article.
Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy.
Strappazzon F, Vietri-Rudan M, Campello S, Nazio F, Florenzano F, Fimia GM, Piacentini M, Levine B, Cecconi F. Strappazzon F, et al. Among authors: campello s. EMBO J. 2011 Apr 6;30(7):1195-208. doi: 10.1038/emboj.2011.49. Epub 2011 Feb 25. EMBO J. 2011. PMID: 21358617 Free PMC article.
56 results