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Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus.
Whitworth KM, Rowland RR, Ewen CL, Trible BR, Kerrigan MA, Cino-Ozuna AG, Samuel MS, Lightner JE, McLaren DG, Mileham AJ, Wells KD, Prather RS. Whitworth KM, et al. Among authors: trible br. Nat Biotechnol. 2016 Jan;34(1):20-2. doi: 10.1038/nbt.3434. Epub 2015 Dec 7. Nat Biotechnol. 2016. PMID: 26641533 No abstract available.
Replacement of Porcine CD163 Scavenger Receptor Cysteine-Rich Domain 5 with a CD163-Like Homolog Confers Resistance of Pigs to Genotype 1 but Not Genotype 2 Porcine Reproductive and Respiratory Syndrome Virus.
Wells KD, Bardot R, Whitworth KM, Trible BR, Fang Y, Mileham A, Kerrigan MA, Samuel MS, Prather RS, Rowland RRR. Wells KD, et al. Among authors: trible br. J Virol. 2017 Jan 3;91(2):e01521-16. doi: 10.1128/JVI.01521-16. Print 2017 Jan 15. J Virol. 2017. PMID: 27847356 Free PMC article.
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