Tsimikas S - Search Results

1

Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides.

Graham MJ, Lee RG, Brandt TA, Tai LJ, Fu W, Peralta R, Yu R, Hurh E, Paz E, McEvoy BW, Baker BF, Pham NC, Digenio A, Hughes SG, Geary RS, Witztum JL, Crooke RM, Tsimikas S. Graham MJ, et al. Among authors: tsimikas s. N Engl J Med. 2017 Jul 20;377(3):222-232. doi: 10.1056/NEJMoa1701329. Epub 2017 May 24. N Engl J Med. 2017. PMID: 28538111 Free article. Clinical Trial.

2

Radiolabeled MDA2, an oxidation-specific, monoclonal antibody, identifies native atherosclerotic lesions in vivo.

Tsimikas S, Palinski W, Halpern SE, Yeung DW, Curtiss LK, Witztum JL. Tsimikas S, et al. J Nucl Cardiol. 1999 Jan-Feb;6(1 Pt 1):41-53. doi: 10.1016/s1071-3581(99)90064-8. J Nucl Cardiol. 1999. PMID: 10070840

3

In vivo uptake of radiolabeled MDA2, an oxidation-specific monoclonal antibody, provides an accurate measure of atherosclerotic lesions rich in oxidized LDL and is highly sensitive to their regression.

Tsimikas S, Shortal BP, Witztum JL, Palinski W. Tsimikas S, et al. Arterioscler Thromb Vasc Biol. 2000 Mar;20(3):689-97. doi: 10.1161/01.atv.20.3.689. Arterioscler Thromb Vasc Biol. 2000. PMID: 10712392

4

Circulating autoantibodies to oxidized LDL correlate with arterial accumulation and depletion of oxidized LDL in LDL receptor-deficient mice.

Tsimikas S, Palinski W, Witztum JL. Tsimikas S, et al. Arterioscler Thromb Vasc Biol. 2001 Jan;21(1):95-100. doi: 10.1161/01.atv.21.1.95. Arterioscler Thromb Vasc Biol. 2001. PMID: 11145939

5

Measuring circulating oxidized low-density lipoprotein to evaluate coronary risk.

Tsimikas S, Witztum JL. Tsimikas S, et al. Circulation. 2001 Apr 17;103(15):1930-2. doi: 10.1161/01.cir.103.15.1930. Circulation. 2001. PMID: 11306518 No abstract available.

6

Human-derived anti-oxidized LDL autoantibody blocks uptake of oxidized LDL by macrophages and localizes to atherosclerotic lesions in vivo.

Shaw PX, Hörkkö S, Tsimikas S, Chang MK, Palinski W, Silverman GJ, Chen PP, Witztum JL. Shaw PX, et al. Among authors: tsimikas s. Arterioscler Thromb Vasc Biol. 2001 Aug;21(8):1333-9. doi: 10.1161/hq0801.093587. Arterioscler Thromb Vasc Biol. 2001. PMID: 11498462

7

Shifting the diagnosis and treatment of atherosclerosis to children and young adults: a new paradigm for the 21st century.

Tsimikas S, Witztum JL. Tsimikas S, et al. J Am Coll Cardiol. 2002 Dec 18;40(12):2122-4. doi: 10.1016/s0735-1097(02)02599-8. J Am Coll Cardiol. 2002. PMID: 12505223 Free article. No abstract available.

8

Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes.

Tsimikas S, Bergmark C, Beyer RW, Patel R, Pattison J, Miller E, Juliano J, Witztum JL. Tsimikas S, et al. J Am Coll Cardiol. 2003 Feb 5;41(3):360-70. doi: 10.1016/s0735-1097(02)02769-9. J Am Coll Cardiol. 2003. PMID: 12575961 Free article.

9

Percutaneous coronary intervention results in acute increases in oxidized phospholipids and lipoprotein(a): short-term and long-term immunologic responses to oxidized low-density lipoprotein.

Tsimikas S, Lau HK, Han KR, Shortal B, Miller ER, Segev A, Curtiss LK, Witztum JL, Strauss BH. Tsimikas S, et al. Circulation. 2004 Jun 29;109(25):3164-70. doi: 10.1161/01.CIR.0000130844.01174.55. Epub 2004 Jun 7. Circulation. 2004. PMID: 15184281

10

High-dose atorvastatin reduces total plasma levels of oxidized phospholipids and immune complexes present on apolipoprotein B-100 in patients with acute coronary syndromes in the MIRACL trial.

Tsimikas S, Witztum JL, Miller ER, Sasiela WJ, Szarek M, Olsson AG, Schwartz GG; Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) Study Investigators. Tsimikas S, et al. Circulation. 2004 Sep 14;110(11):1406-12. doi: 10.1161/01.CIR.0000141728.23033.B5. Epub 2004 Sep 7. Circulation. 2004. PMID: 15353498 Clinical Trial.

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