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Page 1
Investigative safety science as a competitive advantage for Pharma.
Moggs J, Moulin P, Pognan F, Brees D, Leonard M, Busch S, Cordier A, Heard DJ, Kammüller M, Merz M, Bouchard P, Chibout SD. Moggs J, et al. Among authors: cordier a. Expert Opin Drug Metab Toxicol. 2012 Sep;8(9):1071-82. doi: 10.1517/17425255.2012.693914. Epub 2012 Jul 7. Expert Opin Drug Metab Toxicol. 2012. PMID: 22769724 Review.
Vitamin D3 24-hydroxylase mRNA expression in the skin of calcipotriol-treated psoriatic patients correlates with clinical efficacy.
Chibout SD, de Brugerolle de Fraissinette A, Hartmann N, Picarles V, Grenet O, Cordier A, Molloy S, Medina J. Chibout SD, et al. Among authors: cordier a. Arch Dermatol Res. 2003 Nov;295(6):269-71. doi: 10.1007/s00403-003-0428-1. Epub 2003 Sep 23. Arch Dermatol Res. 2003. PMID: 14504887 Clinical Trial. No abstract available.
Induction of hemangiosarcoma in mice after chronic treatment with S1P-modulator siponimod and its lack of relevance to rat and human.
Pognan F, Mahl JA, Papoutsi M, Ledieu D, Raccuglia M, Theil D, Voytek SB, Devine PJ, Kubek-Luck K, Claudio N, Cordier A, Heier A, Kolly C, Hartmann A, Chibout SD, Bouchard P, Trendelenburg C. Pognan F, et al. Among authors: cordier a. Arch Toxicol. 2018 May;92(5):1877-1891. doi: 10.1007/s00204-018-2189-9. Epub 2018 Mar 19. Arch Toxicol. 2018. PMID: 29556671 Free PMC article.
Heart structure-specific transcriptomic atlas reveals conserved microRNA-mRNA interactions.
Vacchi-Suzzi C, Hahne F, Scheubel P, Marcellin M, Dubost V, Westphal M, Boeglen C, Büchmann-Møller S, Cheung MS, Cordier A, De Benedetto C, Deurinck M, Frei M, Moulin P, Oakeley E, Grenet O, Grevot A, Stull R, Theil D, Moggs JG, Marrer E, Couttet P. Vacchi-Suzzi C, et al. Among authors: cordier a. PLoS One. 2013;8(1):e52442. doi: 10.1371/journal.pone.0052442. Epub 2013 Jan 2. PLoS One. 2013. PMID: 23300973 Free PMC article.
Predictivity of an in vitro model for acute and chronic skin irritation (SkinEthic) applied to the testing of topical vehicles.
de Brugerolle de Fraissinette, Picarles V, Chibout S, Kolopp M, Medina J, Burtin P, Ebelin ME, Osborne S, Mayer FK, Spake A, Rosdy M, De Wever B, Ettlin RA, Cordier A. de Brugerolle de Fraissinette, et al. Among authors: cordier a. Cell Biol Toxicol. 1999 Apr;15(2):121-35. doi: 10.1023/a:1007577515215. Cell Biol Toxicol. 1999. PMID: 10408359
Pimecrolimus identifies a common genomic anti-inflammatory profile, is clinically highly effective in psoriasis and is well tolerated.
Rappersberger K, Komar M, Ebelin ME, Scott G, Burtin P, Greig G, Kehren J, Chibout SD, Cordier A, Holter W, Richter L, Oberbauer R, Stuetz A, Wolff K. Rappersberger K, et al. Among authors: cordier a. J Invest Dermatol. 2002 Oct;119(4):876-87. doi: 10.1046/j.1523-1747.2002.00694.x. J Invest Dermatol. 2002. PMID: 12406334 Free article. Clinical Trial.
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