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A double-blind randomised controlled investigation into the efficacy of Mirococept (APT070) for preventing ischaemia reperfusion injury in the kidney allograft (EMPIRIKAL): study protocol for a randomised controlled trial.
Kassimatis T, Qasem A, Douiri A, Ryan EG, Rebollo-Mesa I, Nichols LL, Greenlaw R, Olsburgh J, Smith RA, Sacks SH, Drage M. Kassimatis T, et al. Among authors: sacks sh. Trials. 2017 Jun 6;18(1):255. doi: 10.1186/s13063-017-1972-x. Trials. 2017. PMID: 28587616 Free PMC article. Clinical Trial.
Ex vivo delivery of Mirococept: A dose-finding study in pig kidney after showing a low dose is insufficient to reduce delayed graft function in human kidney.
Kassimatis T, Greenlaw R, Hunter JP, Douiri A, Flach C, Rebollo-Mesa I, Nichols LL, Qasem A, Danzi G, Olsburgh J, Drage M, Friend PJ, Neri F, Karegli J, Horsfield C, Smith RA, Sacks SH. Kassimatis T, et al. Among authors: sacks sh. Am J Transplant. 2021 Mar;21(3):1012-1026. doi: 10.1111/ajt.16265. Epub 2020 Oct 1. Am J Transplant. 2021. PMID: 33225626 Free article.
Targeting complement at the time of transplantation.
Sacks S, Karegli J, Farrar CA, Asgari E, Schwaeble W, Zhou W, Smith RA. Sacks S, et al. Adv Exp Med Biol. 2013;735:247-55. doi: 10.1007/978-1-4614-4118-2_17. Adv Exp Med Biol. 2013. PMID: 23402032 Review.
Development of a multivariable gene-expression signature targeting T-cell-mediated rejection in peripheral blood of kidney transplant recipients validated in cross-sectional and longitudinal samples.
Christakoudi S, Runglall M, Mobillo P, Tsui TL, Duff C, Domingo-Vila C, Kamra Y, Delaney F, Montero R, Spiridou A, Kassimatis T, Phin-Kon S, Tucker B, Farmer C, Strom TB, Lord GM, Rebollo-Mesa I, Stahl D, Sacks S, Hernandez-Fuentes MP, Chowdhury P. Christakoudi S, et al. EBioMedicine. 2019 Mar;41:571-583. doi: 10.1016/j.ebiom.2019.01.060. Epub 2019 Mar 2. EBioMedicine. 2019. PMID: 30833191 Free PMC article.
218 results