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Genetic adaptation of skin pigmentation in highland Tibetans.
Yang Z, Bai C, Pu Y, Kong Q, Guo Y; Ouzhuluobu; Gengdeng; Liu X, Zhao Q, Qiu Z, Zheng W, He Y, Lin Y, Deng L, Zhang C, Xu S, Peng Y, Xiang K, Zhang X; Baimayangji; Cirenyangji; Cui C; Baimakangzhuo; Gonggalanzi; Bianba; Pan Y, Xin J, Wang Y, Liu S, Wang L, Guo H, Feng Z, Wang S, Shi H, Jiang B, Wu T, Qi X, Su B. Yang Z, et al. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2200421119. doi: 10.1073/pnas.2200421119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161951 Free PMC article.
Cross-altitude analysis suggests a turning point at the elevation of 4,500 m for polycythemia prevalence in Tibetans.
Zhang H, He Y, Cui C, Ouzhuluobu, Baimakangzhuo, Duojizhuoma, Dejiquzong, Bianba, Gonggalanzi, Pan Y, Qula, Kangmin, Cirenyangji, Baimayangji, Bai C, Guo W, Yangla, Peng Y, Zhang X, Xiang K, Yang Z, Liu S, Tao X, Gengdeng, Zheng W, Guo Y, Wu T, Qi X, Su B. Zhang H, et al. Am J Hematol. 2017 Sep;92(9):E552-E554. doi: 10.1002/ajh.24809. Epub 2017 Jul 19. Am J Hematol. 2017. PMID: 28589696 Free article. No abstract available.
Down-Regulation of EPAS1 Transcription and Genetic Adaptation of Tibetans to High-Altitude Hypoxia.
Peng Y, Cui C, He Y, Ouzhuluobu, Zhang H, Yang D, Zhang Q, Bianbazhuoma, Yang L, He Y, Xiang K, Zhang X, Bhandari S, Shi P, Yangla, Dejiquzong, Baimakangzhuo, Duojizhuoma, Pan Y, Cirenyangji, Baimayangji, Gonggalanzi, Bai C, Bianba, Basang, Ciwangsangbu, Xu S, Chen H, Liu S, Wu T, Qi X, Su B. Peng Y, et al. Mol Biol Evol. 2017 Apr 1;34(4):818-830. doi: 10.1093/molbev/msw280. Mol Biol Evol. 2017. PMID: 28096303 Free PMC article.
HMOX2 Functions as a Modifier Gene for High-Altitude Adaptation in Tibetans.
Yang D, Peng Y, Ouzhuluobu, Bianbazhuoma, Cui C, Bianba, Wang L, Xiang K, He Y, Zhang H, Zhang X, Liu J, Shi H, Pan Y, Duojizhuoma, Dejiquzong, Cirenyangji, Baimakangzhuo, Gonggalanzi, Liu S, Gengdeng, Wu T, Chen H, Qi X, Su B. Yang D, et al. Hum Mutat. 2016 Feb;37(2):216-23. doi: 10.1002/humu.22935. Epub 2015 Dec 14. Hum Mutat. 2016. PMID: 26781569