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Sembragiline: A Novel, Selective Monoamine Oxidase Type B Inhibitor for the Treatment of Alzheimer's Disease.
Borroni E, Bohrmann B, Grueninger F, Prinssen E, Nave S, Loetscher H, Chinta SJ, Rajagopalan S, Rane A, Siddiqui A, Ellenbroek B, Messer J, Pähler A, Andersen JK, Wyler R, Cesura AM. Borroni E, et al. Among authors: pahler a. J Pharmacol Exp Ther. 2017 Sep;362(3):413-423. doi: 10.1124/jpet.117.241653. Epub 2017 Jun 22. J Pharmacol Exp Ther. 2017. PMID: 28642233
Metabotropic glutamate receptor 5 negative allosteric modulators: discovery of 2-chloro-4-[1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazol-4-ylethynyl]pyridine (basimglurant, RO4917523), a promising novel medicine for psychiatric diseases.
Jaeschke G, Kolczewski S, Spooren W, Vieira E, Bitter-Stoll N, Boissin P, Borroni E, Büttelmann B, Ceccarelli S, Clemann N, David B, Funk C, Guba W, Harrison A, Hartung T, Honer M, Huwyler J, Kuratli M, Niederhauser U, Pähler A, Peters JU, Petersen A, Prinssen E, Ricci A, Rueher D, Rueher M, Schneider M, Spurr P, Stoll T, Tännler D, Wichmann J, Porter RH, Wettstein JG, Lindemann L. Jaeschke G, et al. Among authors: pahler a. J Med Chem. 2015 Feb 12;58(3):1358-71. doi: 10.1021/jm501642c. Epub 2015 Feb 2. J Med Chem. 2015. PMID: 25565255
Discovery and Characterization of 2-Aminooxazolines as Highly Potent, Selective, and Orally Active TAAR1 Agonists.
Galley G, Beurier A, Décoret G, Goergler A, Hutter R, Mohr S, Pähler A, Schmid P, Türck D, Unger R, Zbinden KG, Hoener MC, Norcross RD. Galley G, et al. Among authors: pahler a. ACS Med Chem Lett. 2015 Dec 30;7(2):192-7. doi: 10.1021/acsmedchemlett.5b00449. eCollection 2016 Feb 11. ACS Med Chem Lett. 2015. PMID: 26985297 Free PMC article.
Determination of dalcetrapib by liquid chromatography-tandem mass spectrometry.
Heinig K, Bucheli F, Kuhlmann O, Zell M, Pähler A, Zwanziger E, Gross G, Tardio J, Ishikawa T, Yamashita T. Heinig K, et al. Among authors: pahler a. J Pharm Biomed Anal. 2012 Jul;66:314-24. doi: 10.1016/j.jpba.2012.03.056. Epub 2012 Apr 6. J Pharm Biomed Anal. 2012. PMID: 22541249
51 results