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Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state.
Chaffer CL, Brueckmann I, Scheel C, Kaestli AJ, Wiggins PA, Rodrigues LO, Brooks M, Reinhardt F, Su Y, Polyak K, Arendt LM, Kuperwasser C, Bierie B, Weinberg RA. Chaffer CL, et al. Among authors: weinberg ra. Proc Natl Acad Sci U S A. 2011 May 10;108(19):7950-5. doi: 10.1073/pnas.1102454108. Epub 2011 Apr 15. Proc Natl Acad Sci U S A. 2011. PMID: 21498687 Free PMC article.
Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition.
Shaul YD, Freinkman E, Comb WC, Cantor JR, Tam WL, Thiru P, Kim D, Kanarek N, Pacold ME, Chen WW, Bierie B, Possemato R, Reinhardt F, Weinberg RA, Yaffe MB, Sabatini DM. Shaul YD, et al. Among authors: weinberg ra. Cell. 2014 Aug 28;158(5):1094-1109. doi: 10.1016/j.cell.2014.07.032. Cell. 2014. PMID: 25171410 Free PMC article.
Inflammation Triggers Zeb1-Dependent Escape from Tumor Latency.
De Cock JM, Shibue T, Dongre A, Keckesova Z, Reinhardt F, Weinberg RA. De Cock JM, et al. Among authors: weinberg ra. Cancer Res. 2016 Dec 1;76(23):6778-6784. doi: 10.1158/0008-5472.CAN-16-0608. Epub 2016 Aug 16. Cancer Res. 2016. PMID: 27530323 Free PMC article.
LACTB is a tumour suppressor that modulates lipid metabolism and cell state.
Keckesova Z, Donaher JL, De Cock J, Freinkman E, Lingrell S, Bachovchin DA, Bierie B, Tischler V, Noske A, Okondo MC, Reinhardt F, Thiru P, Golub TR, Vance JE, Weinberg RA. Keckesova Z, et al. Among authors: weinberg ra. Nature. 2017 Mar 30;543(7647):681-686. doi: 10.1038/nature21408. Epub 2017 Mar 22. Nature. 2017. PMID: 28329758 Free PMC article.
448 results