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A non-canonical role of ELN protects from cellular senescence by limiting iron-dependent regulation of gene expression.
Czarnecka-Herok J, Zhu K, Flaman JM, Goehrig D, Vernier M, Makulyte G, Lamboux A, Dragic H, Rhinn M, Médard JJ, Faury G, Bertolino P, Balter V, Debret R, Adnot S, Martin N, Bernard D. Czarnecka-Herok J, et al. Among authors: bertolino p. Redox Biol. 2024 May 22;73:103204. doi: 10.1016/j.redox.2024.103204. Online ahead of print. Redox Biol. 2024. PMID: 38810421 Free article.
Soft extracellular matrix drives endoplasmic reticulum stress-dependent S quiescence underlying molecular traits of pulmonary basal cells.
Laval PA, Piecyk M, Guen PL, Ilie MD, Marion A, Fauvre J, Coste I, Renno T, Aznar N, Hadji C, Migdal C, Duret C, Bertolino P, Ferraro-Peyret C, Nicolas A, Chaveroux C. Laval PA, et al. Among authors: bertolino p. Acta Biomater. 2024 May 23:S1742-7061(24)00272-1. doi: 10.1016/j.actbio.2024.05.033. Online ahead of print. Acta Biomater. 2024. PMID: 38788988 Free article.
A homoeostatic switch causing glycerol-3-phosphate and phosphoethanolamine accumulation triggers senescence by rewiring lipid metabolism.
Tighanimine K, Nabuco Leva Ferreira Freitas JA, Nemazanyy I, Bankolé A, Benarroch-Popivker D, Brodesser S, Doré G, Robinson L, Benit P, Ladraa S, Saada YB, Friguet B, Bertolino P, Bernard D, Canaud G, Rustin P, Gilson E, Bischof O, Fumagalli S, Pende M. Tighanimine K, et al. Among authors: bertolino p. Nat Metab. 2024 Feb;6(2):323-342. doi: 10.1038/s42255-023-00972-y. Epub 2024 Feb 19. Nat Metab. 2024. PMID: 38409325 Free PMC article.
Stiffness-induced cancer-associated fibroblasts are responsible for immunosuppression in a platelet-derived growth factor ligand-dependent manner.
Gamradt P, Thierry K, Masmoudi M, Wu Z, Hernandez-Vargas H, Bachy S, Antonio T, Savas B, Hussain Z, Tomasini R, Milani P, Bertolino P, Hennino A. Gamradt P, et al. Among authors: bertolino p. PNAS Nexus. 2023 Dec 18;2(12):pgad405. doi: 10.1093/pnasnexus/pgad405. eCollection 2023 Dec. PNAS Nexus. 2023. PMID: 38111825 Free PMC article.
Loss of Pla2r1 decreases cellular senescence and age-related alterations caused by aging and Western diets.
Massemin A, Goehrig D, Flaman JM, Jaber S, Griveau A, Djebali S, Marcos E, Payen L, Marvel J, Parent R, Adnot S, Bertolino P, Rieusset J, Tortereau A, Vindrieux D, Bernard D. Massemin A, et al. Among authors: bertolino p. Aging Cell. 2023 Nov;22(11):e13971. doi: 10.1111/acel.13971. Epub 2023 Sep 4. Aging Cell. 2023. PMID: 37667516 Free PMC article.
mRNA vaccine against malaria tailored for liver-resident memory T cells.
Ganley M, Holz LE, Minnell JJ, de Menezes MN, Burn OK, Poa KCY, Draper SL, English K, Chan STS, Anderson RJ, Compton BJ, Marshall AJ, Cozijnsen A, Chua YC, Ge Z, Farrand KJ, Mamum JC, Xu C, Cockburn IA, Yui K, Bertolino P, Gras S, Le Nours J, Rossjohn J, Fernandez-Ruiz D, McFadden GI, Ackerley DF, Painter GF, Hermans IF, Heath WR. Ganley M, et al. Among authors: bertolino p. Nat Immunol. 2023 Sep;24(9):1487-1498. doi: 10.1038/s41590-023-01562-6. Epub 2023 Jul 20. Nat Immunol. 2023. PMID: 37474653
178 results