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Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer.
Sahin U, Derhovanessian E, Miller M, Kloke BP, Simon P, Löwer M, Bukur V, Tadmor AD, Luxemburger U, Schrörs B, Omokoko T, Vormehr M, Albrecht C, Paruzynski A, Kuhn AN, Buck J, Heesch S, Schreeb KH, Müller F, Ortseifer I, Vogler I, Godehardt E, Attig S, Rae R, Breitkreuz A, Tolliver C, Suchan M, Martic G, Hohberger A, Sorn P, Diekmann J, Ciesla J, Waksmann O, Brück AK, Witt M, Zillgen M, Rothermel A, Kasemann B, Langer D, Bolte S, Diken M, Kreiter S, Nemecek R, Gebhardt C, Grabbe S, Höller C, Utikal J, Huber C, Loquai C, Türeci Ö. Sahin U, et al. Among authors: miller m. Nature. 2017 Jul 13;547(7662):222-226. doi: 10.1038/nature23003. Epub 2017 Jul 5. Nature. 2017. PMID: 28678784
Exploiting natural killer cells for therapy of melanoma.
Hölsken O, Miller M, Cerwenka A. Hölsken O, et al. Among authors: miller m. J Dtsch Dermatol Ges. 2015 Jan;13(1):23-9. doi: 10.1111/ddg.12557. J Dtsch Dermatol Ges. 2015. PMID: 25640488 Review. English, German.
Mechanisms of efficacy in cancer immunotherapy: 14th Annual Meeting of the Association for Cancer Immunotherapy (CIMT), Mainz, Germany, May 10-12, 2016.
Theelen J, Braun J, Hörzer H, Kloke BP, Ott M, Pizzitola I, Schirmer U, Miller M. Theelen J, et al. Among authors: miller m. Cancer Immunol Immunother. 2017 May;66(5):673-681. doi: 10.1007/s00262-017-1974-2. Epub 2017 Mar 1. Cancer Immunol Immunother. 2017. PMID: 28251274 Free PMC article. No abstract available.
The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration.
Gdynia G, Sauer SW, Kopitz J, Fuchs D, Duglova K, Ruppert T, Miller M, Pahl J, Cerwenka A, Enders M, Mairbäurl H, Kamiński MM, Penzel R, Zhang C, Fuller JC, Wade RC, Benner A, Chang-Claude J, Brenner H, Hoffmeister M, Zentgraf H, Schirmacher P, Roth W. Gdynia G, et al. Among authors: miller m. Nat Commun. 2016 Mar 7;7:10764. doi: 10.1038/ncomms10764. Nat Commun. 2016. PMID: 26948869 Free PMC article.
Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8.
Walle T, Kraske JA, Liao B, Lenoir B, Timke C, von Bohlen Und Halbach E, Tran F, Griebel P, Albrecht D, Ahmed A, Suarez-Carmona M, Jiménez-Sánchez A, Beikert T, Tietz-Dahlfuß A, Menevse AN, Schmidt G, Brom M, Pahl JHW, Antonopoulos W, Miller M, Perez RL, Bestvater F, Giese NA, Beckhove P, Rosenstiel P, Jäger D, Strobel O, Pe'er D, Halama N, Debus J, Cerwenka A, Huber PE. Walle T, et al. Among authors: miller m. Sci Adv. 2022 Mar 25;8(12):eabh4050. doi: 10.1126/sciadv.abh4050. Epub 2022 Mar 23. Sci Adv. 2022. PMID: 35319989 Free PMC article. Clinical Trial.
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