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Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.
Bushell E, Gomes AR, Sanderson T, Anar B, Girling G, Herd C, Metcalf T, Modrzynska K, Schwach F, Martin RE, Mather MW, McFadden GI, Parts L, Rutledge GG, Vaidya AB, Wengelnik K, Rayner JC, Billker O. Bushell E, et al. Among authors: mcfadden gi. Cell. 2017 Jul 13;170(2):260-272.e8. doi: 10.1016/j.cell.2017.06.030. Cell. 2017. PMID: 28708996 Free PMC article.
Genome sequence of the human malaria parasite Plasmodium falciparum.
Gardner MJ, Hall N, Fung E, White O, Berriman M, Hyman RW, Carlton JM, Pain A, Nelson KE, Bowman S, Paulsen IT, James K, Eisen JA, Rutherford K, Salzberg SL, Craig A, Kyes S, Chan MS, Nene V, Shallom SJ, Suh B, Peterson J, Angiuoli S, Pertea M, Allen J, Selengut J, Haft D, Mather MW, Vaidya AB, Martin DM, Fairlamb AH, Fraunholz MJ, Roos DS, Ralph SA, McFadden GI, Cummings LM, Subramanian GM, Mungall C, Venter JC, Carucci DJ, Hoffman SL, Newbold C, Davis RW, Fraser CM, Barrell B. Gardner MJ, et al. Among authors: mcfadden gi. Nature. 2002 Oct 3;419(6906):498-511. doi: 10.1038/nature01097. Nature. 2002. PMID: 12368864 Free PMC article.
A novel genetic technique in Plasmodium berghei allows liver stage analysis of genes required for mosquito stage development and demonstrates that de novo heme synthesis is essential for liver stage development in the malaria parasite.
Rathnapala UL, Goodman CD, McFadden GI. Rathnapala UL, et al. Among authors: mcfadden gi. PLoS Pathog. 2017 Jun 15;13(6):e1006396. doi: 10.1371/journal.ppat.1006396. eCollection 2017 Jun. PLoS Pathog. 2017. PMID: 28617870 Free PMC article.
214 results