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Drug targets from genetics: α-synuclein.
Danzer KM, McLean PJ. Danzer KM, et al. Among authors: mclean pj. CNS Neurol Disord Drug Targets. 2011 Sep 1;10(6):712-23. doi: 10.2174/187152711797247867. CNS Neurol Disord Drug Targets. 2011. PMID: 21838671 Free PMC article. Review.
Exosomal cell-to-cell transmission of alpha synuclein oligomers.
Danzer KM, Kranich LR, Ruf WP, Cagsal-Getkin O, Winslow AR, Zhu L, Vanderburg CR, McLean PJ. Danzer KM, et al. Among authors: mclean pj. Mol Neurodegener. 2012 Aug 24;7:42. doi: 10.1186/1750-1326-7-42. Mol Neurodegener. 2012. PMID: 22920859 Free PMC article.
Chronic treatment with novel small molecule Hsp90 inhibitors rescues striatal dopamine levels but not α-synuclein-induced neuronal cell loss.
McFarland NR, Dimant H, Kibuuka L, Ebrahimi-Fakhari D, Desjardins CA, Danzer KM, Danzer M, Fan Z, Schwarzschild MA, Hirst W, McLean PJ. McFarland NR, et al. Among authors: mclean pj. PLoS One. 2014 Jan 20;9(1):e86048. doi: 10.1371/journal.pone.0086048. eCollection 2014. PLoS One. 2014. PMID: 24465863 Free PMC article.
Alpha-synuclein and tau: teammates in neurodegeneration?
Moussaud S, Jones DR, Moussaud-Lamodière EL, Delenclos M, Ross OA, McLean PJ. Moussaud S, et al. Among authors: mclean pj. Mol Neurodegener. 2014 Oct 29;9:43. doi: 10.1186/1750-1326-9-43. Mol Neurodegener. 2014. PMID: 25352339 Free PMC article. Review.
Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization.
Eschbach J, von Einem B, Müller K, Bayer H, Scheffold A, Morrison BE, Rudolph KL, Thal DR, Witting A, Weydt P, Otto M, Fauler M, Liss B, McLean PJ, Spada AR, Ludolph AC, Weishaupt JH, Danzer KM. Eschbach J, et al. Among authors: mclean pj. Ann Neurol. 2015 Jan;77(1):15-32. doi: 10.1002/ana.24294. Epub 2014 Dec 19. Ann Neurol. 2015. PMID: 25363075 Free PMC article.
114 results