Mattern M - Search Results

1

Chemical Approaches to Intervening in Ubiquitin Specific Protease 7 (USP7) Function for Oncology and Immune Oncology Therapies.

Wu J, Kumar S, Wang F, Wang H, Chen L, Arsenault P, Mattern M, Weinstock J. Wu J, et al. Among authors: mattern m. J Med Chem. 2018 Jan 25;61(2):422-443. doi: 10.1021/acs.jmedchem.7b00498. Epub 2017 Aug 18. J Med Chem. 2018. PMID: 28768102 Review.

2

4-Aryl-1,2,3-triazole: a novel template for a reversible methionine aminopeptidase 2 inhibitor, optimized to inhibit angiogenesis in vivo.

Kallander LS, Lu Q, Chen W, Tomaszek T, Yang G, Tew D, Meek TD, Hofmann GA, Schulz-Pritchard CK, Smith WW, Janson CA, Ryan MD, Zhang GF, Johanson KO, Kirkpatrick RB, Ho TF, Fisher PW, Mattern MR, Johnson RK, Hansbury MJ, Winkler JD, Ward KW, Veber DF, Thompson SK. Kallander LS, et al. Among authors: mattern mr. J Med Chem. 2005 Sep 8;48(18):5644-7. doi: 10.1021/jm050408c. J Med Chem. 2005. PMID: 16134930

3

Strategies for the identification of ubiquitin ligase inhibitors.

Goldenberg SJ, Marblestone JG, Mattern MR, Nicholson B. Goldenberg SJ, et al. Biochem Soc Trans. 2010 Feb;38(Pt 1):132-6. doi: 10.1042/BST0380132. Biochem Soc Trans. 2010. PMID: 20074047 Free PMC article. Review.

4

Characterization of selective ubiquitin and ubiquitin-like protease inhibitors using a fluorescence-based multiplex assay format.

Tian X, Isamiddinova NS, Peroutka RJ, Goldenberg SJ, Mattern MR, Nicholson B, Leach C. Tian X, et al. Assay Drug Dev Technol. 2011 Apr;9(2):165-73. doi: 10.1089/adt.2010.0317. Epub 2010 Dec 6. Assay Drug Dev Technol. 2011. PMID: 21133675 Free PMC article.

5

Ubiquitin-based anticancer therapy: carpet bombing with proteasome inhibitors vs surgical strikes with E1, E2, E3, or DUB inhibitors.

Mattern MR, Wu J, Nicholson B. Mattern MR, et al. Biochim Biophys Acta. 2012 Nov;1823(11):2014-21. doi: 10.1016/j.bbamcr.2012.05.005. Epub 2012 May 17. Biochim Biophys Acta. 2012. PMID: 22610084 Free PMC article.

6

Discovery of Therapeutic Deubiquitylase Effector Molecules: Current Perspectives.

Nicholson B, Kumar S, Agarwal S, Eddins MJ, Marblestone JG, Wu J, Kodrasov MP, LaRocque JP, Sterner DE, Mattern MR. Nicholson B, et al. Among authors: mattern mr. J Biomol Screen. 2014 Aug;19(7):989-99. doi: 10.1177/1087057114527312. Epub 2014 Mar 14. J Biomol Screen. 2014. PMID: 24632661 Review.

7

Selective Dual Inhibitors of the Cancer-Related Deubiquitylating Proteases USP7 and USP47.

Weinstock J, Wu J, Cao P, Kingsbury WD, McDermott JL, Kodrasov MP, McKelvey DM, Suresh Kumar KG, Goldenberg SJ, Mattern MR, Nicholson B. Weinstock J, et al. Among authors: mattern mr. ACS Med Chem Lett. 2012 Sep 11;3(10):789-92. doi: 10.1021/ml200276j. eCollection 2012 Oct 11. ACS Med Chem Lett. 2012. PMID: 24900381 Free PMC article.

8

Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60.

Wang F, Wang L, Wu J, Sokirniy I, Nguyen P, Bregnard T, Weinstock J, Mattern M, Bezsonova I, Hancock WW, Kumar S. Wang F, et al. Among authors: mattern m. PLoS One. 2017 Dec 13;12(12):e0189744. doi: 10.1371/journal.pone.0189744. eCollection 2017. PLoS One. 2017. PMID: 29236775 Free PMC article.

9

TAM receptors attenuate murine NK-cell responses via E3 ubiquitin ligase Cbl-b.

Chirino LM, Kumar S, Okumura M, Sterner DE, Mattern M, Butt TR, Kambayashi T. Chirino LM, et al. Among authors: mattern m. Eur J Immunol. 2020 Jan;50(1):48-55. doi: 10.1002/eji.201948204. Epub 2019 Sep 30. Eur J Immunol. 2020. PMID: 31531847 Free PMC article.

10

Deubiquitinating enzymes as novel anticancer targets.

Nicholson B, Marblestone JG, Butt TR, Mattern MR. Nicholson B, et al. Future Oncol. 2007 Apr;3(2):191-9. doi: 10.2217/14796694.3.2.191. Future Oncol. 2007. PMID: 17381419 Free PMC article. Review.

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