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Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function.
Piwecka M, Glažar P, Hernandez-Miranda LR, Memczak S, Wolf SA, Rybak-Wolf A, Filipchyk A, Klironomos F, Cerda Jara CA, Fenske P, Trimbuch T, Zywitza V, Plass M, Schreyer L, Ayoub S, Kocks C, Kühn R, Rosenmund C, Birchmeier C, Rajewsky N. Piwecka M, et al. Science. 2017 Sep 22;357(6357):eaam8526. doi: 10.1126/science.aam8526. Epub 2017 Aug 10. Science. 2017. PMID: 28798046
Quantitative proteomics reveals dynamic interaction of c-Jun N-terminal kinase (JNK) with RNA transport granule proteins splicing factor proline- and glutamine-rich (Sfpq) and non-POU domain-containing octamer-binding protein (Nono) during neuronal differentiation.
Sury MD, McShane E, Hernandez-Miranda LR, Birchmeier C, Selbach M. Sury MD, et al. Mol Cell Proteomics. 2015 Jan;14(1):50-65. doi: 10.1074/mcp.M114.039370. Epub 2014 Oct 17. Mol Cell Proteomics. 2015. PMID: 25326457 Free PMC article.
CO₂ in the spotlight.
Hernandez-Miranda LR, Birchmeier C. Hernandez-Miranda LR, et al. Elife. 2015 May 13;4:e08086. doi: 10.7554/eLife.08086. Elife. 2015. PMID: 25970131 Free PMC article.
Neuregulin-1 controls an endogenous repair mechanism after spinal cord injury.
Bartus K, Galino J, James ND, Hernandez-Miranda LR, Dawes JM, Fricker FR, Garratt AN, McMahon SB, Ramer MS, Birchmeier C, Bennett DL, Bradbury EJ. Bartus K, et al. Brain. 2016 May;139(Pt 5):1394-416. doi: 10.1093/brain/aww039. Epub 2016 Mar 17. Brain. 2016. PMID: 26993800 Free PMC article.
Mutations in Disordered Regions Can Cause Disease by Creating Dileucine Motifs.
Meyer K, Kirchner M, Uyar B, Cheng JY, Russo G, Hernandez-Miranda LR, Szymborska A, Zauber H, Rudolph IM, Willnow TE, Akalin A, Haucke V, Gerhardt H, Birchmeier C, Kühn R, Krauss M, Diecke S, Pascual JM, Selbach M. Meyer K, et al. Among authors: hernandez miranda lr. Cell. 2018 Sep 20;175(1):239-253.e17. doi: 10.1016/j.cell.2018.08.019. Epub 2018 Sep 6. Cell. 2018. PMID: 30197081 Free article.
Mutation in LBX1/Lbx1 precludes transcription factor cooperativity and causes congenital hypoventilation in humans and mice.
Hernandez-Miranda LR, Ibrahim DM, Ruffault PL, Larrosa M, Balueva K, Müller T, Weerd W, Stolte-Dijkstra I, Hostra RMW, Brunet JF, Fortin G, Mundlos S, Birchmeier C. Hernandez-Miranda LR, et al. Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):13021-13026. doi: 10.1073/pnas.1813520115. Epub 2018 Nov 28. Proc Natl Acad Sci U S A. 2018. PMID: 30487221 Free PMC article.
Context-specific regulation of cell survival by a miRNA-controlled BIM rheostat.
Labi V, Peng S, Klironomos F, Munschauer M, Kastelic N, Chakraborty T, Schoeler K, Derudder E, Martella M, Mastrobuoni G, Hernandez-Miranda LR, Lahmann I, Kocks C, Birchmeier C, Kempa S, Quintanilla-Martinez de Fend L, Landthaler M, Rajewsky N, Rajewsky K. Labi V, et al. Among authors: hernandez miranda lr. Genes Dev. 2019 Dec 1;33(23-24):1673-1687. doi: 10.1101/gad.330134.119. Epub 2019 Nov 7. Genes Dev. 2019. PMID: 31699777 Free PMC article.
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