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The normal trachea is cleaned by MUC5B mucin bundles from the submucosal glands coated with the MUC5AC mucin.
Ermund A, Meiss LN, Rodriguez-Pineiro AM, Bähr A, Nilsson HE, Trillo-Muyo S, Ridley C, Thornton DJ, Wine JJ, Hebert H, Klymiuk N, Hansson GC. Ermund A, et al. Among authors: meiss ln. Biochem Biophys Res Commun. 2017 Oct 21;492(3):331-337. doi: 10.1016/j.bbrc.2017.08.113. Epub 2017 Aug 30. Biochem Biophys Res Commun. 2017. PMID: 28859985 Free PMC article.
OligoG CF-5/20 normalizes cystic fibrosis mucus by chelating calcium.
Ermund A, Recktenwald CV, Skjåk-Braek G, Meiss LN, Onsøyen E, Rye PD, Dessen A, Myrset AH, Hansson GC. Ermund A, et al. Among authors: meiss ln. Clin Exp Pharmacol Physiol. 2017 Jun;44(6):639-647. doi: 10.1111/1440-1681.12744. Clin Exp Pharmacol Physiol. 2017. PMID: 28261854