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Association of toxicity of sorafenib and sunitinib for human keratinocytes with inhibition of signal transduction and activator of transcription 3 (STAT3).
Yamamoto K, Mizumoto A, Nishimura K, Uda A, Mukai A, Yamashita K, Kume M, Makimoto H, Bito T, Nishigori C, Nakagawa T, Hirano T, Hirai M. Yamamoto K, et al. Among authors: hirano t. PLoS One. 2014 Jul 11;9(7):e102110. doi: 10.1371/journal.pone.0102110. eCollection 2014. PLoS One. 2014. PMID: 25013907 Free PMC article.
Prostaglandin E1 reduces the keratinocyte toxicity of sorafenib by maintaining signal transducer and activator of transcription 3 (STAT3) activity and enhancing the cAMP response element binding protein (CREB) activity.
Shichiri H, Yamamoto K, Tokura M, Ishida T, Uda A, Bito T, Nishigori C, Nakagawa T, Hirano T, Yano I, Hirai M. Shichiri H, et al. Among authors: hirano t. Biochem Biophys Res Commun. 2017 Apr 1;485(2):227-233. doi: 10.1016/j.bbrc.2017.02.107. Epub 2017 Feb 24. Biochem Biophys Res Commun. 2017. PMID: 28237700
Association of Single Nucleotide Polymorphisms in STAT3 with Hand-Foot Skin Reactions in Patients with Metastatic Renal Cell Carcinoma Treated with Multiple Tyrosine Kinase Inhibitors: A Retrospective Analysis in Japanese Patients.
Yamamoto K, Shinomiya K, Ioroi T, Hirata S, Harada K, Suno M, Nishioka T, Kume M, Makimoto H, Nakagawa T, Hirano T, Bito T, Nishigori C, Miyake H, Fujisawa M, Hirai M. Yamamoto K, et al. Among authors: hirano t. Target Oncol. 2016 Feb;11(1):93-9. doi: 10.1007/s11523-015-0382-9. Target Oncol. 2016. PMID: 26300443
STAT3 polymorphism rs4796793 may be a predictive factor of tumor response to multiple tyrosine kinase inhibitors in metastatic renal cell carcinoma in Japanese population.
Yamamoto K, Ioroi T, Kanaya K, Shinomiya K, Komoto S, Hirata S, Harada K, Watanabe A, Suno M, Nishioka T, Kume M, Makimoto H, Nakagawa T, Hirano T, Miyake H, Fujisawa M, Hirai M. Yamamoto K, et al. Among authors: hirano t. Med Oncol. 2016 Mar;33(3):24. doi: 10.1007/s12032-016-0733-0. Epub 2016 Jan 30. Med Oncol. 2016. PMID: 26833481
4,204 results