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Intrinsic fluorescence of the clinically approved multikinase inhibitor nintedanib reveals lysosomal sequestration as resistance mechanism in FGFR-driven lung cancer.
J Exp Clin Cancer Res. 2017 Sep 7;36(1):122. doi: 10.1186/s13046-017-0592-3.
J Exp Clin Cancer Res. 2017.
PMID: 28882160
Free PMC article.
The naturally born fusariotoxin enniatin B and sorafenib exert synergistic activity against cervical cancer in vitro and in vivo.
Dornetshuber-Fleiss R, Heilos D, Mohr T, Richter L, Süssmuth RD, Zlesak M, Novicky A, Heffeter P, Lemmens-Gruber R, Berger W.
Dornetshuber-Fleiss R, et al. Among authors: heilos d.
Biochem Pharmacol. 2015 Feb 1;93(3):318-331. doi: 10.1016/j.bcp.2014.12.013. Epub 2014 Dec 31.
Biochem Pharmacol. 2015.
PMID: 25557295
Free PMC article.
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The Natural Fungal Metabolite Beauvericin Exerts Anticancer Activity In Vivo: A Pre-Clinical Pilot Study.
Heilos D, Rodríguez-Carrasco Y, Englinger B, Timelthaler G, van Schoonhoven S, Sulyok M, Boecker S, Süssmuth RD, Heffeter P, Lemmens-Gruber R, Dornetshuber-Fleiss R, Berger W.
Heilos D, et al.
Toxins (Basel). 2017 Aug 24;9(9):258. doi: 10.3390/toxins9090258.
Toxins (Basel). 2017.
PMID: 28837057
Free PMC article.
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Altered membrane rigidity via enhanced endogenous cholesterol synthesis drives cancer cell resistance to destruxins.
Heilos D, Röhrl C, Pirker C, Englinger B, Baier D, Mohr T, Schwaiger M, Iqbal SM, van Schoonhoven S, Klavins K, Eberhart T, Windberger U, Taibon J, Sturm S, Stuppner H, Koellensperger G, Dornetshuber-Fleiss R, Jäger W, Lemmens-Gruber R, Berger W.
Heilos D, et al.
Oncotarget. 2018 May 22;9(39):25661-25680. doi: 10.18632/oncotarget.25432. eCollection 2018 May 22.
Oncotarget. 2018.
PMID: 29876015
Free PMC article.
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Mouse tissue distribution and persistence of the food-born fusariotoxins Enniatin B and Beauvericin.
Rodríguez-Carrasco Y, Heilos D, Richter L, Süssmuth RD, Heffeter P, Sulyok M, Kenner L, Berger W, Dornetshuber-Fleiss R.
Rodríguez-Carrasco Y, et al. Among authors: heilos d.
Toxicol Lett. 2016 Apr 15;247:35-44. doi: 10.1016/j.toxlet.2016.02.008. Epub 2016 Feb 15.
Toxicol Lett. 2016.
PMID: 26892719
Free PMC article.
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EVI1 inhibits apoptosis induced by antileukemic drugs via upregulation of CDKN1A/p21/WAF in human myeloid cells.
Rommer A, Steinmetz B, Herbst F, Hackl H, Heffeter P, Heilos D, Filipits M, Steinleitner K, Hemmati S, Herbacek I, Schwarzinger I, Hartl K, Rondou P, Glimm H, Karakaya K, Krämer A, Berger W, Wieser R.
Rommer A, et al. Among authors: heilos d.
PLoS One. 2013;8(2):e56308. doi: 10.1371/journal.pone.0056308. Epub 2013 Feb 14.
PLoS One. 2013.
PMID: 23457546
Free PMC article.
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Changed genome heterochromatinization upon prolonged activation of the Raf/ERK signaling pathway.
Martin C, Chen S, Heilos D, Sauer G, Hunt J, Shaw AG, Sims PF, Jackson DA, Lovrić J.
Martin C, et al. Among authors: heilos d.
PLoS One. 2010 Oct 12;5(10):e13322. doi: 10.1371/journal.pone.0013322.
PLoS One. 2010.
PMID: 20967285
Free PMC article.
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