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Novel multi-targeting anthra[2,3-b]thiophene-5,10-diones with guanidine-containing side chains: interaction with telomeric G-quadruplex, inhibition of telomerase and topoisomerase I and cytotoxic properties.
Ilyinsky NS, Shchyolkina AK, Borisova OF, Mamaeva OK, Zvereva MI, Azhibek DM, Livshits MA, Mitkevich VA, Balzarini J, Sinkevich YB, Luzikov YN, Dezhenkova LG, Kolotova ES, Shtil AA, Shchekotikhin AE, Kaluzhny DN. Ilyinsky NS, et al. Among authors: kaluzhny dn. Eur J Med Chem. 2014 Oct 6;85:605-14. doi: 10.1016/j.ejmech.2014.08.030. Epub 2014 Aug 8. Eur J Med Chem. 2014. PMID: 25127152
Synthesis and evaluation of new antitumor 3-aminomethyl-4,11-dihydroxynaphtho[2,3-f]indole-5,10-diones.
Shchekotikhin AE, Glazunova VA, Dezhenkova LG, Luzikov YN, Buyanov VN, Treshalina HM, Lesnaya NA, Romanenko VI, Kaluzhny DN, Balzarini J, Agama K, Pommier Y, Shtil AA, Preobrazhenskaya MN. Shchekotikhin AE, et al. Among authors: kaluzhny dn. Eur J Med Chem. 2014 Oct 30;86:797-805. doi: 10.1016/j.ejmech.2014.09.021. Epub 2014 Sep 8. Eur J Med Chem. 2014. PMID: 25244612
Discovery of antitumor anthra[2,3-b]furan-3-carboxamides: Optimization of synthesis and evaluation of antitumor properties.
Shchekotikhin AE, Dezhenkova LG, Tsvetkov VB, Luzikov YN, Volodina YL, Tatarskiy VV Jr, Kalinina AA, Treshalin MI, Treshalina HM, Romanenko VI, Kaluzhny DN, Kubbutat M, Schols D, Pommier Y, Shtil AA, Preobrazhenskaya MN. Shchekotikhin AE, et al. Among authors: kaluzhny dn. Eur J Med Chem. 2016 Apr 13;112:114-129. doi: 10.1016/j.ejmech.2016.01.050. Epub 2016 Feb 4. Eur J Med Chem. 2016. PMID: 26890118 Free PMC article.
Amides of pyrrole- and thiophene-fused anthraquinone derivatives: A role of the heterocyclic core in antitumor properties.
Tikhomirov AS, Litvinova VA, Andreeva DV, Tsvetkov VB, Dezhenkova LG, Volodina YL, Kaluzhny DN, Treshalin ID, Schols D, Ramonova AA, Moisenovich MM, Shtil AA, Shchekotikhin AE. Tikhomirov AS, et al. Among authors: kaluzhny dn. Eur J Med Chem. 2020 Aug 1;199:112294. doi: 10.1016/j.ejmech.2020.112294. Epub 2020 May 6. Eur J Med Chem. 2020. PMID: 32428792
Thiophene-2-carboxamide derivatives of anthraquinone: A new potent antitumor chemotype.
Volodina YL, Tikhomirov AS, Dezhenkova LG, Ramonova AA, Kononova AV, Andreeva DV, Kaluzhny DN, Schols D, Moisenovich MM, Shchekotikhin AE, Shtil AA. Volodina YL, et al. Among authors: kaluzhny dn. Eur J Med Chem. 2021 Oct 5;221:113521. doi: 10.1016/j.ejmech.2021.113521. Epub 2021 May 24. Eur J Med Chem. 2021. PMID: 34082225
62 results