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ABCG2 regulatory single-nucleotide polymorphisms alter in vivo enhancer activity and expression.
Pharmacogenet Genomics. 2017 Dec;27(12):454-463. doi: 10.1097/FPC.0000000000000312.
Pharmacogenet Genomics. 2017.
PMID: 28930109
Free PMC article.
In Vivo Hepatic Enhancer Elements in the Human ABCG2 Locus.
Eclov RJ, Kim MJ, Smith RP, Liang X, Ahituv N, Kroetz DL.
Eclov RJ, et al.
Drug Metab Dispos. 2017 Feb;45(2):208-215. doi: 10.1124/dmd.116.072033. Epub 2016 Nov 17.
Drug Metab Dispos. 2017.
PMID: 27856528
Free PMC article.
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Rare Variants in the ABCG2 Promoter Modulate In Vivo Activity.
Eclov RJ, Kim MJ, Smith R, Ahituv N, Kroetz DL.
Eclov RJ, et al.
Drug Metab Dispos. 2018 May;46(5):636-642. doi: 10.1124/dmd.117.079541. Epub 2018 Feb 21.
Drug Metab Dispos. 2018.
PMID: 29467213
Free PMC article.
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A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101.
Baldwin RM, Owzar K, Zembutsu H, Chhibber A, Kubo M, Jiang C, Watson D, Eclov RJ, Mefford J, McLeod HL, Friedman PN, Hudis CA, Winer EP, Jorgenson EM, Witte JS, Shulman LN, Nakamura Y, Ratain MJ, Kroetz DL.
Baldwin RM, et al. Among authors: eclov rj.
Clin Cancer Res. 2012 Sep 15;18(18):5099-109. doi: 10.1158/1078-0432.CCR-12-1590. Epub 2012 Jul 27.
Clin Cancer Res. 2012.
PMID: 22843789
Free PMC article.
Clinical Trial.
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Inhibition of FOXP3 by stapled alpha-helical peptides dampens regulatory T cell function.
Hawley KM, Eclov RJ, Schnorenberg MR, Tian Y, Shah RN, Thomas-Toth AT, Fefferman M, Bird GH, Walensky LD, Tirrell MV, LaBelle JL.
Hawley KM, et al. Among authors: eclov rj.
Proc Natl Acad Sci U S A. 2022 Oct 18;119(42):e2209044119. doi: 10.1073/pnas.2209044119. Epub 2022 Oct 13.
Proc Natl Acad Sci U S A. 2022.
PMID: 36227917
Free PMC article.
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