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Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress.
O'Brien KA, McNally BD, Sowton AP, Murgia A, Armitage J, Thomas LW, Krause FN, Maddalena LA, Francis I, Kavanagh S, Williams DP, Ashcroft M, Griffin JL, Lyon JJ, Murray AJ. O'Brien KA, et al. Among authors: lyon jj. BMC Biol. 2021 Dec 15;19(1):265. doi: 10.1186/s12915-021-01192-0. BMC Biol. 2021. PMID: 34911556 Free PMC article.
Pivotal role for two electron reduction in 2,3-dimethoxy-1,4-naphthoquinone and 2-methyl-1,4-naphthoquinone metabolism and kinetics in vivo that prevents liver redox stress.
Parry JD, Pointon AV, Lutz U, Teichert F, Charlwood JK, Chan PH, Athersuch TJ, Taylor EL, Singh R, Luo J, Phillips KM, Vetillard A, Lyon JJ, Keun HC, Lutz WK, Gant TW. Parry JD, et al. Among authors: lyon jj. Chem Res Toxicol. 2009 Apr;22(4):717-25. doi: 10.1021/tx800472z. Chem Res Toxicol. 2009. PMID: 19338340
In vivo assessment of mitochondrial toxicity.
Hamilton BF, Stokes AH, Lyon J, Adler RR. Hamilton BF, et al. Drug Discov Today. 2008 Sep;13(17-18):785-90. doi: 10.1016/j.drudis.2008.05.008. Epub 2008 Jul 4. Drug Discov Today. 2008. PMID: 18577467 Review.
Perturbation of microRNAs in rat heart during chronic doxorubicin treatment.
Vacchi-Suzzi C, Bauer Y, Berridge BR, Bongiovanni S, Gerrish K, Hamadeh HK, Letzkus M, Lyon J, Moggs J, Paules RS, Pognan F, Staedtler F, Vidgeon-Hart MP, Grenet O, Couttet P. Vacchi-Suzzi C, et al. PLoS One. 2012;7(7):e40395. doi: 10.1371/journal.pone.0040395. Epub 2012 Jul 31. PLoS One. 2012. PMID: 22859947 Free PMC article.
21 results