Pastan I - Search Results

1

A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells.

Pastan I, Gottesman MM, Ueda K, Lovelace E, Rutherford AV, Willingham MC. Pastan I, et al. Proc Natl Acad Sci U S A. 1988 Jun;85(12):4486-90. doi: 10.1073/pnas.85.12.4486. Proc Natl Acad Sci U S A. 1988. PMID: 2898143 Free PMC article.

2

The Role of Multidrug Resistance Efflux Pumps in Cancer: Revisiting a JNCI Publication Exploring Expression of the MDR1 (P-glycoprotein) Gene.

Gottesman MM, Pastan IH. Gottesman MM, et al. J Natl Cancer Inst. 2015 Aug 18;107(9):djv222. doi: 10.1093/jnci/djv222. Print 2015 Sep. J Natl Cancer Inst. 2015. PMID: 26286731 Free PMC article. No abstract available.

3

Immunocytochemical localization of P170 at the plasma membrane of multidrug-resistant human cells.

Willingham MC, Richert ND, Cornwell MM, Tsuruo T, Hamada H, Gottesman MM, Pastan IH. Willingham MC, et al. Among authors: pastan ih. J Histochem Cytochem. 1987 Dec;35(12):1451-6. doi: 10.1177/35.12.2890686. J Histochem Cytochem. 1987. PMID: 2890686

4

Expression of a human complementary DNA for the multidrug resistance gene in murine hematopoietic precursor cells with the use of retroviral gene transfer.

McLachlin JR, Eglitis MA, Ueda K, Kantoff PW, Pastan IH, Anderson WF, Gottesman MM. McLachlin JR, et al. Among authors: pastan ih. J Natl Cancer Inst. 1990 Aug 1;82(15):1260-3. doi: 10.1093/jnci/82.15.1260. J Natl Cancer Inst. 1990. PMID: 2374175

5

ATP and GTP as alternative energy sources for vinblastine transport by P-170 in KB-V1 plasma membrane vesicles.

Lelong IH, Padmanabhan R, Lovelace E, Pastan I, Gottesman MM. Lelong IH, et al. Among authors: pastan i. FEBS Lett. 1992 Jun 15;304(2-3):256-60. doi: 10.1016/0014-5793(92)80632-q. FEBS Lett. 1992. PMID: 1352260 Free article.

6

Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis.

Ambudkar SV, Lelong IH, Zhang J, Cardarelli CO, Gottesman MM, Pastan I. Ambudkar SV, et al. Among authors: pastan i. Proc Natl Acad Sci U S A. 1992 Sep 15;89(18):8472-6. doi: 10.1073/pnas.89.18.8472. Proc Natl Acad Sci U S A. 1992. PMID: 1356264 Free PMC article.

7

Identification of residues in the first cytoplasmic loop of P-glycoprotein involved in the function of chimeric human MDR1-MDR2 transporters.

Currier SJ, Kane SE, Willingham MC, Cardarelli CO, Pastan I, Gottesman MM. Currier SJ, et al. Among authors: pastan i. J Biol Chem. 1992 Dec 15;267(35):25153-9. J Biol Chem. 1992. PMID: 1360983 Free article.

8

Transgenic mice that express the human multidrug-resistance gene in bone marrow enable a rapid identification of agents that reverse drug resistance.

Mickisch GH, Merlino GT, Galski H, Gottesman MM, Pastan I. Mickisch GH, et al. Among authors: pastan i. Proc Natl Acad Sci U S A. 1991 Jan 15;88(2):547-51. doi: 10.1073/pnas.88.2.547. Proc Natl Acad Sci U S A. 1991. PMID: 1671173 Free PMC article.

9

Agents which reverse multidrug-resistance are inhibitors of [3H]vinblastine transport by isolated vesicles.

Horio M, Lovelace E, Pastan I, Gottesman MM. Horio M, et al. Among authors: pastan i. Biochim Biophys Acta. 1991 Jan 9;1061(1):106-10. doi: 10.1016/0005-2736(91)90274-c. Biochim Biophys Acta. 1991. PMID: 1671642

We have previously reported that plasma membrane vesicles partially purified from multidrug-resistant human KB carcinoma cells, but not from drug-sensitive cells, accumulated [3H]vinblastine in an ATP-dependent manner (Horio, M., Gottesman, M.M. and Pastan, I. (1988 …

We have previously reported that plasma membrane vesicles partially purified from multidrug-resistant human KB carcinoma cells, but not from …

10

Magnetic-affinity cell sorting of human multidrug-resistant cells.

Padmanabhan R, Tsuruo T, Kane SE, Willingham MC, Howard BH, Gottesman MM, Pastan I. Padmanabhan R, et al. Among authors: pastan i. J Natl Cancer Inst. 1991 Apr 17;83(8):565-9. doi: 10.1093/jnci/83.8.565. J Natl Cancer Inst. 1991. PMID: 1672384

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