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Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer's disease Braak stages: a quantitative study in humans.
Theofilas P, Ehrenberg AJ, Nguy A, Thackrey JM, Dunlop S, Mejia MB, Alho AT, Paraizo Leite RE, Rodriguez RD, Suemoto CK, Nascimento CF, Chin M, Medina-Cleghorn D, Cuervo AM, Arkin M, Seeley WW, Miller BL, Nitrini R, Pasqualucci CA, Filho WJ, Rueb U, Neuhaus J, Heinsen H, Grinberg LT. Theofilas P, et al. Among authors: cuervo am. Neurobiol Aging. 2018 Jan;61:1-12. doi: 10.1016/j.neurobiolaging.2017.09.007. Epub 2017 Sep 20. Neurobiol Aging. 2018. PMID: 29031088 Free PMC article.
Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia.
Geier EG, Bourdenx M, Storm NJ, Cochran JN, Sirkis DW, Hwang JH, Bonham LW, Ramos EM, Diaz A, Van Berlo V, Dokuru D, Nana AL, Karydas A, Balestra ME, Huang Y, Russo SP, Spina S, Grinberg LT, Seeley WW, Myers RM, Miller BL, Coppola G, Lee SE, Cuervo AM, Yokoyama JS. Geier EG, et al. Among authors: cuervo am. Acta Neuropathol. 2019 Jan;137(1):71-88. doi: 10.1007/s00401-018-1925-9. Epub 2018 Oct 31. Acta Neuropathol. 2019. PMID: 30382371 Free PMC article.
Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.
Bourdenx M, Martín-Segura A, Scrivo A, Rodriguez-Navarro JA, Kaushik S, Tasset I, Diaz A, Storm NJ, Xin Q, Juste YR, Stevenson E, Luengo E, Clement CC, Choi SJ, Krogan NJ, Mosharov EV, Santambrogio L, Grueninger F, Collin L, Swaney DL, Sulzer D, Gavathiotis E, Cuervo AM. Bourdenx M, et al. Among authors: cuervo am. Cell. 2021 May 13;184(10):2696-2714.e25. doi: 10.1016/j.cell.2021.03.048. Epub 2021 Apr 22. Cell. 2021. PMID: 33891876 Free PMC article.
Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.
Wang C, Fan L, Khawaja RR, Liu B, Zhan L, Kodama L, Chin M, Li Y, Le D, Zhou Y, Condello C, Grinberg LT, Seeley WW, Miller BL, Mok SA, Gestwicki JE, Cuervo AM, Luo W, Gan L. Wang C, et al. Among authors: cuervo am. Nat Commun. 2022 Apr 12;13(1):1969. doi: 10.1038/s41467-022-29552-6. Nat Commun. 2022. PMID: 35413950 Free PMC article.
293 results