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Efficacy of nerve growth factor antibody in a knee osteoarthritis pain model in mice.
Miyagi M, Ishikawa T, Kamoda H, Suzuki M, Inoue G, Sakuma Y, Oikawa Y, Orita S, Uchida K, Takahashi K, Takaso M, Ohtori S. Miyagi M, et al. Among authors: takahashi k. BMC Musculoskelet Disord. 2017 Nov 3;18(1):428. doi: 10.1186/s12891-017-1792-x. BMC Musculoskelet Disord. 2017. PMID: 29100502 Free PMC article.
Nuclear factor-kappa B decoy suppresses nerve injury and improves mechanical allodynia and thermal hyperalgesia in a rat lumbar disc herniation model.
Suzuki M, Inoue G, Gemba T, Watanabe T, Ito T, Koshi T, Yamauchi K, Yamashita M, Orita S, Eguchi Y, Ochiai N, Kishida S, Takaso M, Aoki Y, Takahashi K, Ohtori S. Suzuki M, et al. Among authors: takahashi k. Eur Spine J. 2009 Jul;18(7):1001-7. doi: 10.1007/s00586-009-0940-x. Epub 2009 Mar 24. Eur Spine J. 2009. PMID: 19308465 Free PMC article.
Low affinity NGF receptor (p75 neurotrophin receptor) inhibitory antibody reduces pain behavior and CGRP expression in DRG in the mouse sciatic nerve crush model.
Fukui Y, Ohtori S, Yamashita M, Yamauchi K, Inoue G, Suzuki M, Orita S, Eguchi Y, Ochiai N, Kishida S, Takaso M, Wakai K, Hayashi Y, Aoki Y, Takahashi K. Fukui Y, et al. Among authors: takahashi k. J Orthop Res. 2010 Mar;28(3):279-83. doi: 10.1002/jor.20986. J Orthop Res. 2010. PMID: 19824062 Free article.
Effect of applying p75NTR saporin to a punctured intervertebral disc on calcitonin gene-related peptide expression in rat dorsal root ganglion neurons.
Sugiura A, Ohtori S, Yamashita M, Yamauchi K, Inoue G, Suzuki M, Norimoto M, Orita S, Eguchi Y, Kuniyoshi K, Ochiai N, Kishida S, Takaso M, Aoki Y, Ishikawa T, Arai G, Miyagi M, Kamoda H, Nakamura J, Takahashi K. Sugiura A, et al. Among authors: takahashi k. J Orthop Sci. 2010 May;15(3):407-13. doi: 10.1007/s00776-010-1469-x. Epub 2010 Jun 18. J Orthop Sci. 2010. PMID: 20559810
Inhibiting nerve growth factor or its receptors downregulates calcitonin gene-related peptide expression in rat lumbar dorsal root ganglia innervating injured intervertebral discs.
Orita S, Ohtori S, Nagata M, Horii M, Yamashita M, Yamauchi K, Inoue G, Suzuki M, Eguchi Y, Kamoda H, Arai G, Ishikawa T, Miyagi M, Ochiai N, Kishida S, Takaso M, Aoki Y, Takahashi K. Orita S, et al. Among authors: takahashi k. J Orthop Res. 2010 Dec;28(12):1614-20. doi: 10.1002/jor.21170. J Orthop Res. 2010. PMID: 20973063 Free article.
Direct application of the tumor necrosis factor-α inhibitor, etanercept, into a punctured intervertebral disc decreases calcitonin gene-related peptide expression in rat dorsal root ganglion neurons.
Horii M, Orita S, Nagata M, Takaso M, Yamauchi K, Yamashita M, Inoue G, Eguchi Y, Ochiai N, Kishida S, Aoki Y, Ishikawa T, Arai G, Miyagi M, Kamoda H, Kuniyoshi K, Suzuki M, Nakamura J, Toyone T, Takahashi K, Ohtori S. Horii M, et al. Among authors: takahashi k. Spine (Phila Pa 1976). 2011 Jan 15;36(2):E80-5. doi: 10.1097/BRS.0b013e3181d4be3c. Spine (Phila Pa 1976). 2011. PMID: 21057386
Disk injury in rats produces persistent increases in pain-related neuropeptides in dorsal root ganglia and spinal cord glia but only transient increases in inflammatory mediators: pathomechanism of chronic diskogenic low back pain.
Miyagi M, Ishikawa T, Orita S, Eguchi Y, Kamoda H, Arai G, Suzuki M, Inoue G, Aoki Y, Toyone T, Takahashi K, Ohtori S. Miyagi M, et al. Among authors: takahashi k. Spine (Phila Pa 1976). 2011 Dec 15;36(26):2260-6. doi: 10.1097/BRS.0b013e31820e68c7. Spine (Phila Pa 1976). 2011. PMID: 21228748
Assessment of gait in a rat model of myofascial inflammation using the CatWalk system.
Miyagi M, Ishikawa T, Kamoda H, Orita S, Kuniyoshi K, Ochiai N, Kishida S, Nakamura J, Eguchi Y, Arai G, Suzuki M, Aoki Y, Toyone T, Takahashi K, Inoue G, Ohtori S. Miyagi M, et al. Among authors: takahashi k. Spine (Phila Pa 1976). 2011 Oct 1;36(21):1760-4. doi: 10.1097/BRS.0b013e3182269732. Spine (Phila Pa 1976). 2011. PMID: 21673621
Pain-related sensory innervation in monoiodoacetate-induced osteoarthritis in rat knees that gradually develops neuronal injury in addition to inflammatory pain.
Orita S, Ishikawa T, Miyagi M, Ochiai N, Inoue G, Eguchi Y, Kamoda H, Arai G, Toyone T, Aoki Y, Kubo T, Takahashi K, Ohtori S. Orita S, et al. Among authors: takahashi k. BMC Musculoskelet Disord. 2011 Jun 16;12:134. doi: 10.1186/1471-2474-12-134. BMC Musculoskelet Disord. 2011. PMID: 21679434 Free PMC article.
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