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A thermostable Cas9 with increased lifetime in human plasma.
Harrington LB, Paez-Espino D, Staahl BT, Chen JS, Ma E, Kyrpides NC, Doudna JA. Harrington LB, et al. Among authors: doudna ja. Nat Commun. 2017 Nov 10;8(1):1424. doi: 10.1038/s41467-017-01408-4. Nat Commun. 2017. PMID: 29127284 Free PMC article.
In vitro reconstitution of the human RISC-loading complex.
MacRae IJ, Ma E, Zhou M, Robinson CV, Doudna JA. MacRae IJ, et al. Among authors: doudna ja. Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):512-7. doi: 10.1073/pnas.0710869105. Epub 2008 Jan 4. Proc Natl Acad Sci U S A. 2008. PMID: 18178619 Free PMC article.
Autoinhibition of human dicer by its internal helicase domain.
Ma E, MacRae IJ, Kirsch JF, Doudna JA. Ma E, et al. Among authors: doudna ja. J Mol Biol. 2008 Jun 27;380(1):237-43. doi: 10.1016/j.jmb.2008.05.005. Epub 2008 May 8. J Mol Biol. 2008. PMID: 18508075 Free PMC article.
Structural insights into RNA processing by the human RISC-loading complex.
Wang HW, Noland C, Siridechadilok B, Taylor DW, Ma E, Felderer K, Doudna JA, Nogales E. Wang HW, et al. Among authors: doudna ja. Nat Struct Mol Biol. 2009 Nov;16(11):1148-53. doi: 10.1038/nsmb.1673. Epub 2009 Oct 11. Nat Struct Mol Biol. 2009. PMID: 19820710 Free PMC article.
RNA-programmed genome editing in human cells.
Jinek M, East A, Cheng A, Lin S, Ma E, Doudna J. Jinek M, et al. Elife. 2013 Jan 29;2:e00471. doi: 10.7554/eLife.00471. Elife. 2013. PMID: 23386978 Free PMC article.
Substrate-specific structural rearrangements of human Dicer.
Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW. Taylor DW, et al. Among authors: doudna ja. Nat Struct Mol Biol. 2013 Jun;20(6):662-70. doi: 10.1038/nsmb.2564. Epub 2013 Apr 28. Nat Struct Mol Biol. 2013. PMID: 23624860 Free PMC article.
384 results