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Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8S Configuration.
Johnson TA, Morris JD, Coppage DA, Cook CV, Persi LN, Ogarrio MA, Garcia TC, McIntosh NL, McCauley EP, Media J, Maheshwari M, Valeriote FA, Shaw J, Crews P. Johnson TA, et al. Among authors: mccauley ep. ACS Med Chem Lett. 2020 Jan 2;11(2):108-113. doi: 10.1021/acsmedchemlett.9b00302. eCollection 2020 Feb 13. ACS Med Chem Lett. 2020. PMID: 32071675 Free PMC article.
Re-evaluation of the Fijianolide/Laulimalide Chemotype Suggests an Alternate Mechanism of Action for C-15/C-20 Analogs.
Morris JD, Takahashi-Ruiz L, Persi LN, Summers JC, McCauley EP, Chan PYW, Amberchan G, Lizama-Chamu I, Coppage DA, Crews P, Risinger AL, Johnson TA. Morris JD, et al. Among authors: mccauley ep. ACS Omega. 2022 Mar 7;7(10):8824-8832. doi: 10.1021/acsomega.1c07146. eCollection 2022 Mar 15. ACS Omega. 2022. PMID: 35309480 Free PMC article.
15 results