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Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies.
Kohrt HE, Thielens A, Marabelle A, Sagiv-Barfi I, Sola C, Chanuc F, Fuseri N, Bonnafous C, Czerwinski D, Rajapaksa A, Waller E, Ugolini S, Vivier E, Romagné F, Levy R, Bléry M, André P. Kohrt HE, et al. Blood. 2014 Jan 30;123(5):678-86. doi: 10.1182/blood-2013-08-519199. Epub 2013 Dec 10. Blood. 2014. PMID: 24326534 Free PMC article.
Ibrutinib antagonizes rituximab-dependent NK cell-mediated cytotoxicity.
Kohrt HE, Sagiv-Barfi I, Rafiq S, Herman SE, Butchar JP, Cheney C, Zhang X, Buggy JJ, Muthusamy N, Levy R, Johnson AJ, Byrd JC. Kohrt HE, et al. Blood. 2014 Mar 20;123(12):1957-60. doi: 10.1182/blood-2014-01-547869. Blood. 2014. PMID: 24652965 Free PMC article. No abstract available.
Depleting tumor-specific Tregs at a single site eradicates disseminated tumors.
Marabelle A, Kohrt H, Sagiv-Barfi I, Ajami B, Axtell RC, Zhou G, Rajapaksa R, Green MR, Torchia J, Brody J, Luong R, Rosenblum MD, Steinman L, Levitsky HI, Tse V, Levy R. Marabelle A, et al. J Clin Invest. 2013 Jun;123(6):2447-63. doi: 10.1172/JCI64859. J Clin Invest. 2013. PMID: 23728179 Free PMC article.
Radiotherapy and toll-like receptor agonists.
Marabelle A, Filatenkov A, Sagiv-Barfi I, Kohrt H. Marabelle A, et al. Semin Radiat Oncol. 2015 Jan;25(1):34-9. doi: 10.1016/j.semradonc.2014.07.006. Semin Radiat Oncol. 2015. PMID: 25481264 Review.
Targeting CD137 enhances the efficacy of cetuximab.
Kohrt HE, Colevas AD, Houot R, Weiskopf K, Goldstein MJ, Lund P, Mueller A, Sagiv-Barfi I, Marabelle A, Lira R, Troutner E, Richards L, Rajapaska A, Hebb J, Chester C, Waller E, Ostashko A, Weng WK, Chen L, Czerwinski D, Fu YX, Sunwoo J, Levy R. Kohrt HE, et al. J Clin Invest. 2014 Jun;124(6):2668-82. doi: 10.1172/JCI73014. Epub 2014 May 16. J Clin Invest. 2014. Retraction in: J Clin Invest. 2019 Jun 03;129(6):2595. doi: 10.1172/JCI129689. PMID: 24837434 Free PMC article. Retracted.
Intratumoral immunotherapy relies on B and T cell collaboration.
Sagiv-Barfi I, Czerwinski DK, Shree T, Lohmeyer JJK, Levy R. Sagiv-Barfi I, et al. Sci Immunol. 2022 May 27;7(71):eabn5859. doi: 10.1126/sciimmunol.abn5859. Epub 2022 May 27. Sci Immunol. 2022. PMID: 35622903 Free PMC article.
21 results